Biomaterial Database

Plasma cortisol and appetitively motivated arousal in monkeys. 1984

B H Natelson, and P E Stokes, and W N Tapp

A disagreement exists in the literature as to whether plasma glucocorticoids are a sensitive index of emotional arousal. In order to provide further data on this subject, arousal in adult male rhesus monkeys was produced by classical appetitive conditioning done once every 48 hr. Monkeys showed significantly more aroused behavior during CS+ sessions than during CS- sessions. Concurrent with these behavioral changes, appetitive conditioning suppressed the increase in plasma cortisol that took place in control conditions. This dissociation between cortisol and arousal provides additional data for the conclusion that plasma glucocorticoids are an insensitive index of arousal. The fact that glucocorticoids decrease dramatically under similar experimental conditions in rats suggests that hormonal regulatory mechanisms for this rodent species may differ from that for primates.

UI	MeSH Term	Description	Entries
D008253	Macaca mulatta	A species of the genus MACACA inhabiting India, China, and other parts of Asia. The species is used extensively in biomedical research and adapts very well to living with humans.	Chinese Rhesus Macaques,Macaca mulatta lasiota,Monkey, Rhesus,Rhesus Monkey,Rhesus Macaque,Chinese Rhesus Macaque,Macaca mulatta lasiotas,Macaque, Rhesus,Rhesus Macaque, Chinese,Rhesus Macaques,Rhesus Macaques, Chinese,Rhesus Monkeys
D008297	Male		Males
D003214	Conditioning, Classical	Learning that takes place when a conditioned stimulus is paired with an unconditioned stimulus.	Reflex, Conditioned,Classical Conditioning,Classical Conditionings,Conditioned Reflex,Conditionings, Classical
D005502	Food	Substances taken in by the body to provide nourishment.	Foods
D006854	Hydrocortisone	The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.	Cortef,Cortisol,Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-,11-Epicortisol,Cortifair,Cortril,Epicortisol,Hydrocortisone, (11 alpha)-Isomer,Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer,11 Epicortisol
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001143	Arousal	Cortical vigilance or readiness of tone, presumed to be in response to sensory stimulation via the reticular activating system.	Vigilance, Cortical,Arousals,Cortical Vigilance
D013016	Sound	A type of non-ionizing radiation in which energy is transmitted through solid, liquid, or gas as compression waves. Sound (acoustic or sonic) radiation with frequencies above the audible range is classified as ultrasonic. Sound radiation below the audible range is classified as infrasonic.	Acoustic Waves,Elastic Waves,Sonic Radiation,Sound Waves,Acoustic Wave,Elastic Wave,Radiation, Sonic,Radiations, Sonic,Sonic Radiations,Sound Wave,Sounds,Wave, Acoustic,Wave, Elastic,Wave, Sound,Waves, Acoustic,Waves, Elastic,Waves, Sound