Inhibition of insulin secretion by exogenous insulin in normal man as demonstrated by C-peptide assay. 1978

J E Liljenquist, and D L Horwitz, and A S Jennings, and J L Chiasson, and U Keller, and A H Rubenstein

UI MeSH Term Description Entries
D007328 Insulin A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin
D008297 Male Males
D010455 Peptides Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are considered to be larger versions of peptides that can form into complex structures such as ENZYMES and RECEPTORS. Peptide,Polypeptide,Polypeptides
D001786 Blood Glucose Glucose in blood. Blood Sugar,Glucose, Blood,Sugar, Blood
D002096 C-Peptide The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin. Proinsulin C-Peptide,C-Peptide, Proinsulin,Connecting Peptide,C Peptide,C Peptide, Proinsulin,Proinsulin C Peptide
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

J E Liljenquist, and D L Horwitz, and A S Jennings, and J L Chiasson, and U Keller, and A H Rubenstein
January 1987, Diabetologia,
J E Liljenquist, and D L Horwitz, and A S Jennings, and J L Chiasson, and U Keller, and A H Rubenstein
November 1977, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
J E Liljenquist, and D L Horwitz, and A S Jennings, and J L Chiasson, and U Keller, and A H Rubenstein
February 1985, Experimental and clinical endocrinology,
J E Liljenquist, and D L Horwitz, and A S Jennings, and J L Chiasson, and U Keller, and A H Rubenstein
December 1982, The Tohoku journal of experimental medicine,
J E Liljenquist, and D L Horwitz, and A S Jennings, and J L Chiasson, and U Keller, and A H Rubenstein
May 1989, Bollettino della Societa italiana di biologia sperimentale,
J E Liljenquist, and D L Horwitz, and A S Jennings, and J L Chiasson, and U Keller, and A H Rubenstein
November 1955, Journal of the American Medical Association,
J E Liljenquist, and D L Horwitz, and A S Jennings, and J L Chiasson, and U Keller, and A H Rubenstein
November 1986, The Journal of clinical investigation,
J E Liljenquist, and D L Horwitz, and A S Jennings, and J L Chiasson, and U Keller, and A H Rubenstein
September 1988, Diabetes,
J E Liljenquist, and D L Horwitz, and A S Jennings, and J L Chiasson, and U Keller, and A H Rubenstein
October 1979, Diabetologia,
J E Liljenquist, and D L Horwitz, and A S Jennings, and J L Chiasson, and U Keller, and A H Rubenstein
May 1976, Gastroenterology,
Copied contents to your clipboard!