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Systolic time intervals have been investigated in 26 subjects with severe liver cirrhosis. The patients were subdivided as follows: 15 with alcoholic cirrhosis; 11 with post-necrotic cirrhosis. Systolic time intervals were recorded and measured according to the Weissler's method. The left ventricular ejection time was significantly shortened due to the low systemic vascular resistance, while the pre-ejection period was unchanged, denoting preserved myocardial contractility. The isometric contraction time was also significantly shortened, thus confirming a good myocardial response to increased pre-load due to hyperdynamic state. The cardiac performance as assessed by systolic time intervals, is unchanged in hepatic cirrhosis.
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