Biomaterial Database

Slipped epiphysis associated with hypothyroidism. 1984

W Heyerman, and D Weiner

Seven cases of slipped capital femoral epiphysis appearing concurrently with juvenile hypothyroidism are reported. This association seems to occur more commonly than the general incidence of slipped capital femoral epiphysis or of juvenile hypothyroidism would suggest, and the thyroid hormone deficiency and a diminished strength of the epiphyseal growth plate of the upper femur appear to be associated. Although concrete scientific data are as yet not available to define clearly the effect of thyroid hormone on the growth plate, the possible pathophysiology is discussed in light of available data.

UI	MeSH Term	Description	Entries
D007037	Hypothyroidism	A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.	Central Hypothyroidism,Primary Hypothyroidism,Secondary Hypothyroidism,TSH Deficiency,Thyroid-Stimulating Hormone Deficiency,Central Hypothyroidisms,Deficiency, TSH,Deficiency, Thyroid-Stimulating Hormone,Hormone Deficiency, Thyroid-Stimulating,Hypothyroidism, Central,Hypothyroidism, Primary,Hypothyroidism, Secondary,Hypothyroidisms,Primary Hypothyroidisms,Secondary Hypothyroidisms,TSH Deficiencies,Thyroid Stimulating Hormone Deficiency,Thyroid-Stimulating Hormone Deficiencies
D008297	Male		Males
D011859	Radiography	Examination of any part of the body for diagnostic purposes by means of X-RAYS or GAMMA RAYS, recording the image on a sensitized surface (such as photographic film).	Radiology, Diagnostic X-Ray,Roentgenography,X-Ray, Diagnostic,Diagnostic X-Ray,Diagnostic X-Ray Radiology,X-Ray Radiology, Diagnostic,Diagnostic X Ray,Diagnostic X Ray Radiology,Diagnostic X-Rays,Radiology, Diagnostic X Ray,X Ray Radiology, Diagnostic,X Ray, Diagnostic,X-Rays, Diagnostic
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D004839	Epiphyses, Slipped	A complete or partial separation of the EPIPHYSES from the DIAPHYSES.	Epiphysiolysis,Epiphysiolyses,Slipped Epiphyses
D005260	Female		Females
D005270	Femur Head	The hemispheric articular surface at the upper extremity of the thigh bone. (Stedman, 26th ed)	Femoral Head,Femoral Heads,Femur Heads,Head, Femoral,Head, Femur
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths