Biomaterial Database

[Influences of the biliary reconstructions by Roux-en Y method and jejunal interposition method on the gastric acid secretion in dogs]. 1984

M Tatsumi

This study was made to examine the influences on the gastric acid secretion and serum gastrin level after the oral administration of beef extract, and on the inhibitory mechanism of the gastric acid secretion after the intraduodenal injection of either lipid or glucose in dogs which had reconstructed biliary tract by means of either Roux-en Y cholecystojejunostomy or cholecystoduodenojejunostomy; jejunal interposition between the gallbladder and the duodenum. The excreted gastric acid secretion from Heidenhain pouch showed a slight increase after cholecystojejunoduodenostomy, while it increased significantly after Roux-en Y cholecystojejunostomy. The serum gastrin showed no significant changes after either reconstruction. The gastric acid secretion after the intraduodenal injection of glucose was inhibited almost to the degree before and after either reconstruction. The inhibitory effects on the gastric acid secretion after the intraduodenal injection of lipid were not observed after Roux-en Y cholecystojejunostomy but it was significantly inhibited after cholecystojejunoduodenostomy. It can be concluded from these results that jejunal interposition will be more suitable for the gastric acid secretion or its inhibitory mechanism than Roux-en Y type.

UI	MeSH Term	Description	Entries
D007583	Jejunum	The middle portion of the SMALL INTESTINE, between DUODENUM and ILEUM. It represents about 2/5 of the remaining portion of the small intestine below duodenum.	Jejunums
D008297	Male		Males
D008722	Methods	A series of steps taken in order to conduct research.	Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D004386	Duodenum	The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers.	Duodenums
D005260	Female		Females
D005704	Gallbladder	A storage reservoir for BILE secretion. Gallbladder allows the delivery of bile acids at a high concentration and in a controlled manner, via the CYSTIC DUCT to the DUODENUM, for degradation of dietary lipid.	Gallbladders
D005744	Gastric Acid	Hydrochloric acid present in GASTRIC JUICE.	Hydrochloric Acid, Gastric,Acids, Gastric,Acids, Gastric Hydrochloric,Gastric Acids,Gastric Hydrochloric Acid,Gastric Hydrochloric Acids,Hydrochloric Acids, Gastric
D005755	Gastrins	A family of gastrointestinal peptide hormones that excite the secretion of GASTRIC JUICE. They may also occur in the central nervous system where they are presumed to be neurotransmitters.	Gastrin
D005947	Glucose	A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.	Dextrose,Anhydrous Dextrose,D-Glucose,Glucose Monohydrate,Glucose, (DL)-Isomer,Glucose, (alpha-D)-Isomer,Glucose, (beta-D)-Isomer,D Glucose,Dextrose, Anhydrous,Monohydrate, Glucose