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The ability of gastric preloads of milk, water, and isotonic saline to inhibit ingestion was studied in deprived 6-day-old rat pups being fed through oral cannulas. Preloads were delivered through gastric cannulas or by gavage, and both the volume of the load and the interval between the preload and testing were varied in order to assess the relative contributions of pre- and post-absorptive cues from the loads. Pups' willingness to initiate ingestion in short (10 min) tests (appetite) was unaffected by the degree of gastric filling produced by a load but was depressed by post-absorptive changes in hydrational state. On the other hand, pups terminated ingestion in long (30 min) tests (satiety) in response to gastric filling. Cessation of intake in long tests was only slightly influenced by post-absorptive factors. These results reveal two distinct phases of ingestion in infant rats and show that each is controlled in a different manner.
W G Hall, and
J P Bruno
May 1986,
The American journal of physiology,
W G Hall, and
J P Bruno
November 1986,
Behavioral and neural biology,
W G Hall, and
J P Bruno
August 1996,
Physiology & behavior,
W G Hall, and
J P Bruno
June 1995,
Behavioral neuroscience,
W G Hall, and
J P Bruno
July 1979,
Science (New York, N.Y.),
W G Hall, and
J P Bruno
December 1981,
Science (New York, N.Y.),
W G Hall, and
J P Bruno
March 1982,
Pharmacology, biochemistry, and behavior,
W G Hall, and
J P Bruno
September 1991,
Physiology & behavior,
W G Hall, and
J P Bruno
June 2001,
East African medical journal,
W G Hall, and
J P Bruno
November 1998,
Neuroscience letters,
