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The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. Data from animal studies have been examined from the standpoint of dose-response relationships and the sensitivity of various animal species, including man, to the effects of this chemical. In view of recent findings with other chemically related glycol ethers, particular attention has been given to possible adverse effects on blood and testicular tissue. In evaluating the hazard that this chemical may pose to man, consideration has been given to likely routes of exposure and its irritant properties. It is concluded that the available information continues to support the current ACGIH TWA8-TLV of 25 ppm with a STEL of 75 ppm.
T R Tyler
February 1986,
Fundamental and applied toxicology : official journal of the Society of Toxicology,
T R Tyler
August 1984,
Environmental health perspectives,
T R Tyler
April 1991,
MMWR. Morbidity and mortality weekly report,
T R Tyler
February 1997,
Environmental health perspectives,
T R Tyler
January 2002,
Toxicology mechanisms and methods,
T R Tyler
August 1984,
Environmental health perspectives,
T R Tyler
January 1992,
Journal of toxicology. Clinical toxicology,
T R Tyler
January 1987,
Teratogenesis, carcinogenesis, and mutagenesis,
T R Tyler
April 1990,
Bulletin of environmental contamination and toxicology,
T R Tyler
July 1987,
The Journal of pharmacology and experimental therapeutics,
