Biomaterial Database

[Hemorheologic therapy in peripheral arterial occlusive disease]. 1984

H Kiesewetter, and F Jung

In view of current knowledge drug treatment of peripheral arterial occlusive disease is required at stage IIb in most cases. Angiological diagnostic procedures should be conducted to determine the location and extent of occlusion as well as to evaluate the blood fluidity. Rheological therapy is indicated in cases of microangiopathy, inoperable macroangiopathy, pre- and postoperative treatment of macroangiopathy and macroangiopathy after angioplasty or fibrinolysis. Drug treatment is administered according to clinical status and rheological parameters. The main emphasis in therapy includes hemodilution, reducing the fibrinogen concentration and improvement of blood fluidity. The findings of hemodilution therapy with various hydroxy-ethyl starches as well as a monotherapy with naftidrofuryl are presented and discussed.

UI	MeSH Term	Description	Entries
D006973	Hypertension	Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.	Blood Pressure, High,Blood Pressures, High,High Blood Pressure,High Blood Pressures
D007866	Leg	The inferior part of the lower extremity between the KNEE and the ANKLE.	Legs
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009257	Nafronyl	A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.	Nafronyloxalate,Naftidrofuryl,Artocoron,Azunaftil,Di-Actane,Dusodril,Gévatran,LS-121,Nafronyl Oxalate,Nafti Von Ct,Nafti-Puren,Nafti-Ratiopharm,Naftifurin Oxalate,Naftilong,Naftilux,Praxilene,Praxilène,Di Actane,LS 121,LS121,Nafti Puren,Nafti Ratiopharm,NaftiRatiopharm,Oxalate, Nafronyl,Oxalate, Naftifurin
D003131	Combined Modality Therapy	The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.	Multimodal Treatment,Therapy, Combined Modality,Combined Modality Therapies,Modality Therapies, Combined,Modality Therapy, Combined,Multimodal Treatments,Therapies, Combined Modality,Treatment, Multimodal,Treatments, Multimodal
D006400	Hematocrit	The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.	Erythrocyte Volume, Packed,Packed Red-Cell Volume,Erythrocyte Volumes, Packed,Hematocrits,Packed Erythrocyte Volume,Packed Erythrocyte Volumes,Packed Red Cell Volume,Packed Red-Cell Volumes,Red-Cell Volume, Packed,Red-Cell Volumes, Packed,Volume, Packed Erythrocyte,Volume, Packed Red-Cell,Volumes, Packed Erythrocyte,Volumes, Packed Red-Cell
D006438	Hemodilution	Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.	Hemodilutions
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly