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Two human melanoma cell lines, extremely different in their thermal sensitivity, were pulse-labelled with (35S)-methionine after 60 min of exposure at 42 degrees C. For both cell lines, fractionation of the intrinsically labelled proteins by polyacrylamide gel electrophoresis (PAGE) showed increased labelling of a polypeptide band of Mr 72,000, along with a slight reduction of overall protein synthesis. By two-dimensional electrophoresis, the Mr 72,000 band resolved into multiple pattern components of the same size but differing in isoelectric points. The absence of qualitative and quantitative differences between the two melanoma cell lines indicates that the different thermal sensitivities are unrelated to their ability to express the heat-shock proteins.
U Ferrini, and
R Falcioni, and
A Delpino, and
R Cavaliere, and
G Zupi, and
P G Natali
November 1994,
Cancer letters,
U Ferrini, and
R Falcioni, and
A Delpino, and
R Cavaliere, and
G Zupi, and
P G Natali
January 1990,
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine,
U Ferrini, and
R Falcioni, and
A Delpino, and
R Cavaliere, and
G Zupi, and
P G Natali
March 2015,
Human & experimental toxicology,
U Ferrini, and
R Falcioni, and
A Delpino, and
R Cavaliere, and
G Zupi, and
P G Natali
September 2016,
Oncology reports,
U Ferrini, and
R Falcioni, and
A Delpino, and
R Cavaliere, and
G Zupi, and
P G Natali
April 1973,
Journal of the National Cancer Institute,
U Ferrini, and
R Falcioni, and
A Delpino, and
R Cavaliere, and
G Zupi, and
P G Natali
December 1990,
The American journal of tropical medicine and hygiene,
U Ferrini, and
R Falcioni, and
A Delpino, and
R Cavaliere, and
G Zupi, and
P G Natali
December 1995,
The Journal of dermatology,
U Ferrini, and
R Falcioni, and
A Delpino, and
R Cavaliere, and
G Zupi, and
P G Natali
October 1996,
Biochemical and biophysical research communications,
U Ferrini, and
R Falcioni, and
A Delpino, and
R Cavaliere, and
G Zupi, and
P G Natali
September 1992,
Experimental cell research,
U Ferrini, and
R Falcioni, and
A Delpino, and
R Cavaliere, and
G Zupi, and
P G Natali
October 1987,
Cytotechnology,
