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The effect of PS-K as immunomodulator was studied in Fischer rats bearing neurogenic tumors induced transplacentally by ENU. 114 rats were divided into control and PS-K treated groups. all rats were subjected to an autopsy at death and all of central nervous system were examined macroscopically. Final neurogenic tumor incidence in PS-K treated groups was significantly lower than that in the control group, but distribution of these neurogenic tumors and number of neurogenic tumors in a rat remained unchanged between the control and the each PS-K treated groups. Survival time of PS-K treated groups did not increase than the control group. From these experiments, it might be that induction of neurogenic tumors may be suppressed by administration of PS-K.
K Tokuda, and
H Abe, and
T Aida, and
S Kaneko, and
M Tsuru
August 2005,
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie,
K Tokuda, and
H Abe, and
T Aida, and
S Kaneko, and
M Tsuru
June 1981,
The Kobe journal of medical sciences,
K Tokuda, and
H Abe, and
T Aida, and
S Kaneko, and
M Tsuru
October 1975,
Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology,
K Tokuda, and
H Abe, and
T Aida, and
S Kaneko, and
M Tsuru
January 1978,
Arkhiv patologii,
K Tokuda, and
H Abe, and
T Aida, and
S Kaneko, and
M Tsuru
January 1977,
No to shinkei = Brain and nerve,
K Tokuda, and
H Abe, and
T Aida, and
S Kaneko, and
M Tsuru
September 1977,
Nihon geka hokan. Archiv fur japanische Chirurgie,
K Tokuda, and
H Abe, and
T Aida, and
S Kaneko, and
M Tsuru
January 1982,
Journal of cancer research and clinical oncology,
K Tokuda, and
H Abe, and
T Aida, and
S Kaneko, and
M Tsuru
May 1989,
Journal of neuropathology and experimental neurology,
K Tokuda, and
H Abe, and
T Aida, and
S Kaneko, and
M Tsuru
August 1966,
Die Naturwissenschaften,
K Tokuda, and
H Abe, and
T Aida, and
S Kaneko, and
M Tsuru
May 1978,
European journal of cancer,
