Biomaterial Database

Pseudophakic bullous keratopathy. Relationship to preoperative corneal endothelial status. 1984

G N Rao, and J V Aquavella, and S H Goldberg, and S L Berk

Pseudophakic bullous keratopathy is one of the complications of intraocular lens implantation. A knowledge of the preoperative status of corneal endothelium may help to minimize the incidence of this complication. The preoperative corneal endothelial status of 118 eyes of 102 patients who received Worst-Medallion intraocular lenses more than five years ago was analyzed retrospectively. This data was then correlated with the postoperative clinical status of the cornea. Twelve eyes (10%) underwent penetrating keratoplasty for irreversible corneal edema, and 28 of the remaining eyes (22%) had clinical evidence of peripheral corneal edema. No correlation was found between the preoperative endothelial cell density or the degree of postoperative cell loss and the development of corneal edema. Significant correlation was found between variation in cell size (pleomorphism) and the development of postoperative corneal edema. Greater density of precipitates on endothelium and abnormality in cell shape postoperatively were also frequently seen in corneas that developed edema subsequently.

UI	MeSH Term	Description	Entries
D007634	Keratitis	Inflammation of the cornea.	Keratitides
D007910	Lenses, Intraocular	Artificial implanted lenses.	Implantable Contact Lens,Lens, Intraocular,Contact Lens, Implantable,Intraocular Lens,Intraocular Lenses,Lens, Implantable Contact
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011183	Postoperative Complications	Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D002452	Cell Count	The number of CELLS of a specific kind, usually measured per unit volume or area of sample.	Cell Density,Cell Number,Cell Counts,Cell Densities,Cell Numbers,Count, Cell,Counts, Cell,Densities, Cell,Density, Cell,Number, Cell,Numbers, Cell
D003315	Cornea	The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)	Corneas
D004487	Edema	Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.	Dropsy,Hydrops,Anasarca
D004727	Endothelium	A layer of epithelium that lines the heart, blood vessels (ENDOTHELIUM, VASCULAR), lymph vessels (ENDOTHELIUM, LYMPHATIC), and the serous cavities of the body.	Endotheliums
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly