The clinical significance of strain gauge plethysmography in pampiniform plexus pathology has been explored, with the assumption that there should be some analogy with lower limb venous conditions in which this examination gives valuable results. The first findings seem to confirm that strain gauge plethysmography affords, in varicocele, some reliable evaluations on venous drainage insufficiency, capacity and resiliency of spermatic venous bed as well as on functional results of surgical treatment.