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Serum dopamine-beta-hydroxylase (DBH) activity was tested in 160 psychiatric patients suffering from affective disorders. The patients were divided into subgroups according to strict diagnostic criteria and clinical state at the time of the examination. Since no relationship was found between DBH activity and age or sex, these variables have been discarded from further analyses. Bipolar (manic-depressive) patients had lower (p less than 0.05) BDH mean values than patients suffering from unipolar, recurrent depressive psychoses. No other differences were found either among group or in relation to the clinical state. As such a wide range of DBH values was recorded in all the groups examined, measurements of DBH activity do not seem to be useful as a diagnostic acid, or as an indicator of the clinical state of patients suffering from affective disorders.
E Strandman, and
L Wetterberg, and
C Perris, and
S B Ross
March 1976,
Psychopharmacologia,
E Strandman, and
L Wetterberg, and
C Perris, and
S B Ross
October 1984,
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E Strandman, and
L Wetterberg, and
C Perris, and
S B Ross
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The Journal of clinical endocrinology and metabolism,
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L Wetterberg, and
C Perris, and
S B Ross
June 1978,
Pharmacological reviews,
E Strandman, and
L Wetterberg, and
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March 1971,
Circulation research,
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January 1974,
The New Zealand medical journal,
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March 1986,
Acta psychiatrica Scandinavica,
E Strandman, and
L Wetterberg, and
C Perris, and
S B Ross
January 1977,
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L Wetterberg, and
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June 1975,
The Journal of laboratory and clinical medicine,
E Strandman, and
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Psychological medicine,
