Alternative preparation of methyl 3-amino-2,3,6-trideoxy-alpha-D-arabino-hexopyranoside and chiral intermediates for the synthesis of thienamycin.
1984
A O Stewart, and
R M Williams
UI
MeSH Term
Description
Entries
D006595
Hexosamines
AMINO SUGARS created by adding an amine group to a hexose sugar.
Hexosamine
D013845
Thienamycins
Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors.