BIOMAT Database Logo BIOMAT Database Logo

1-Halophenyl-N,N'-di-(2-heteroaryl)-methylendiamines and 1-halophenyl-3-(2-heteroaryl)-thiazolidin-4-ones as potential hypotensive agents. 1984

A Chimirri, and S Grasso, and G Fenech, and P Monforte, and C Circosta, and F Occhiuto, and S Ragusa

UI MeSH Term Description Entries
D007928 Lethal Dose 50 The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population. LD50,Dose 50, Lethal
D008297 Male Males
D002621 Chemistry A basic science concerned with the composition, structure, and properties of matter; and the reactions that occur between substances and the associated energy exchange.
D003959 Diamines Organic chemicals which have two amino groups in an aliphatic chain. Diamine
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000959 Antihypertensive Agents Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. Anti-Hypertensive,Anti-Hypertensive Agent,Anti-Hypertensive Drug,Antihypertensive,Antihypertensive Agent,Antihypertensive Drug,Anti-Hypertensive Agents,Anti-Hypertensive Drugs,Anti-Hypertensives,Antihypertensive Drugs,Antihypertensives,Agent, Anti-Hypertensive,Agent, Antihypertensive,Agents, Anti-Hypertensive,Agents, Antihypertensive,Anti Hypertensive,Anti Hypertensive Agent,Anti Hypertensive Agents,Anti Hypertensive Drug,Anti Hypertensive Drugs,Anti Hypertensives,Drug, Anti-Hypertensive,Drug, Antihypertensive,Drugs, Anti-Hypertensive,Drugs, Antihypertensive
D013844 Thiazoles Heterocyclic compounds where the ring system is composed of three CARBON atoms, a SULFUR and NITROGEN atoms. Thiazole
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus
D055598 Chemical Phenomena The composition, structure, conformation, and properties of atoms and molecules, and their reaction and interaction processes. Chemical Concepts,Chemical Processes,Physical Chemistry Concepts,Physical Chemistry Processes,Physicochemical Concepts,Physicochemical Phenomena,Physicochemical Processes,Chemical Phenomenon,Chemical Process,Physical Chemistry Phenomena,Physical Chemistry Process,Physicochemical Phenomenon,Physicochemical Process,Chemical Concept,Chemistry Process, Physical,Chemistry Processes, Physical,Concept, Chemical,Concept, Physical Chemistry,Concept, Physicochemical,Concepts, Chemical,Concepts, Physical Chemistry,Concepts, Physicochemical,Phenomena, Chemical,Phenomena, Physical Chemistry,Phenomena, Physicochemical,Phenomenon, Chemical,Phenomenon, Physicochemical,Physical Chemistry Concept,Physicochemical Concept,Process, Chemical,Process, Physical Chemistry,Process, Physicochemical,Processes, Chemical,Processes, Physical Chemistry,Processes, Physicochemical

Related Publications

A Chimirri, and S Grasso, and G Fenech, and P Monforte, and C Circosta, and F Occhiuto, and S Ragusa
2-(2,6-Dihalo-phenyl)-3-heteroaryl-2-ylmethyl-1, 3-thiazolidin-4-ones: anti-HIV agents.
August 2008, Chemical biology & drug design,
A Chimirri, and S Grasso, and G Fenech, and P Monforte, and C Circosta, and F Occhiuto, and S Ragusa
Design and synthesis of 2-(2,6-dibromophenyl)-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents.
December 2008, European journal of medicinal chemistry,
A Chimirri, and S Grasso, and G Fenech, and P Monforte, and C Circosta, and F Occhiuto, and S Ragusa
Design, synthesis, and evaluation of 2-aryl-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents.
February 2007, Bioorganic & medicinal chemistry,
A Chimirri, and S Grasso, and G Fenech, and P Monforte, and C Circosta, and F Occhiuto, and S Ragusa
Thiazolidin-4-Ones as Potential Antimicrobial Agents: Experimental and In Silico Evaluation.
March 2022, Molecules (Basel, Switzerland),
A Chimirri, and S Grasso, and G Fenech, and P Monforte, and C Circosta, and F Occhiuto, and S Ragusa
Synthesis and biological evaluation of novel 2-heteroarylimino-1,3-thiazolidin-4-ones as potential anti-tumor agents.
April 2015, European journal of medicinal chemistry,
A Chimirri, and S Grasso, and G Fenech, and P Monforte, and C Circosta, and F Occhiuto, and S Ragusa
Design and synthesis of 3-[(7-chloro-1-oxidoquinolin-4-ylamino)alkyl]-1,3-thiazolidin-4-ones as antimalarial agents.
October 2013, Journal of enzyme inhibition and medicinal chemistry,
A Chimirri, and S Grasso, and G Fenech, and P Monforte, and C Circosta, and F Occhiuto, and S Ragusa
Dehydroabietylamine-based thiazolidin-4-ones and 2-thioxoimidazolidin-4-ones as novel tyrosyl-DNA phosphodiesterase 1 inhibitors.
November 2021, Molecular diversity,
A Chimirri, and S Grasso, and G Fenech, and P Monforte, and C Circosta, and F Occhiuto, and S Ragusa
Synthesis of thiazolidin-4-ones and thiazinan-4-ones from 1-(2-aminoethyl)pyrrolidine as acetylcholinesterase inhibitors.
December 2020, Journal of enzyme inhibition and medicinal chemistry,
A Chimirri, and S Grasso, and G Fenech, and P Monforte, and C Circosta, and F Occhiuto, and S Ragusa
Facile synthesis of 1,3-thiazolidin-4-ones as antitubercular agents.
April 2016, Bioorganic & medicinal chemistry letters,
A Chimirri, and S Grasso, and G Fenech, and P Monforte, and C Circosta, and F Occhiuto, and S Ragusa
Ovicidal in vitro activity of 2-aryl-3-(2-morpholinoethyl)thiazolidin-4-ones and 2-aryl-3-(3-morpholinopropyl)thiazolidin-4-ones against Fasciola hepatica (Linnaeus, 1758).
September 2018, Experimental parasitology,
Copied contents to your clipboard!