Studies on the excretion of endogenously formed N-nitrosoproline. I. Percutaneous excretion of N-nitrosoproline in humans. 1984

P A Bogovski, and M A Rooma, and J M Kann

N-Nitrosoproline (NPRO) formed intragastrically after ingestion of 8 mg/kg body weight sodium nitrate and the same amount of proline was determined in the sweat of six volunteers during intensive sweating in a Finnish sauna (60-80 degrees C). The amounts of sweat and NPRO and the concentrations of this compound varied between individual volunteers and in the same subjects in consecutive experiments. Females excreted higher concentrations of NPRO in smaller amounts of sweat. During the second hour after the start of intragastric nitrosation of proline, the concentrations and amounts of NPRO in sweat decreased rapidly.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009566 Nitrates Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical. Nitrate
D009602 Nitrosamines A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties. Nitrosamine
D011392 Proline A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons. L-Proline,L Proline
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D013542 Sweat The fluid excreted by the SWEAT GLANDS. It consists of water containing sodium chloride, phosphate, urea, ammonia, and other waste products. Sweats

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