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The effect of local anesthetics pentacaine ((+/-)-trans N-/2-(3-pentyloxy-phenylcarbamoyloxy)-cyclohexyl/- pyrrolidinium chloride), heptacaine (N-/2-(2-heptyloxy-phenyl-carbamoyloxy)-ethyl/-piperidini um chloride) and trimecaine (2, 4, 6-trimethylphenylcarbamoyl)-methyldiethylammonium chloride) on granulation tissue formation in open skin wounds was examined in rats. The anesthetics applied on the wounds 3 times a day for 5 days caused increase in granulation tissue weight, in DNA and hydroxyproline contents. Pentacaine had the most pronounced effects (190% dry weight, 253% DNA and 148% hydroxyproline content when compared to saline-treated controls). The smallest changes were observed after heptacaine treatment.
J Kanta, and
L Kopácová, and
M Patocková, and
F Bartos
January 1980,
Acta chirurgica Scandinavica,
J Kanta, and
L Kopácová, and
M Patocková, and
F Bartos
May 1963,
Wiener klinische Wochenschrift,
J Kanta, and
L Kopácová, and
M Patocková, and
F Bartos
January 1980,
Acta chirurgica Scandinavica,
J Kanta, and
L Kopácová, and
M Patocková, and
F Bartos
January 1962,
Annales medicinae experimentalis et biologiae Fenniae,
J Kanta, and
L Kopácová, and
M Patocková, and
F Bartos
December 1957,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
J Kanta, and
L Kopácová, and
M Patocková, and
F Bartos
July 1956,
A.M.A. archives of pathology,
J Kanta, and
L Kopácová, and
M Patocková, and
F Bartos
January 1981,
Experimental pathology,
J Kanta, and
L Kopácová, and
M Patocková, and
F Bartos
May 1963,
Wiener klinische Wochenschrift,
J Kanta, and
L Kopácová, and
M Patocková, and
F Bartos
January 1960,
Journal of dental research,
J Kanta, and
L Kopácová, and
M Patocková, and
F Bartos
January 1953,
Journal international de chirurgie,
