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In adult male rats treated with streptozotocin 6 weeks before the experiments, androgen-binding protein concentration was increased in testicular tissue by 33% (p less than 0.01) and reduced in epididymal tissue by 25% (p less than 0.005) in animals exhibiting severe hyperglycaemia as compared with animals remaining in normoglycaemia or moderate hyperglycaemia. Androgen-binding protein content was diminished in epididymal tissue by 40% (p less than 0.0005) but not changed in testicular tissue. If related to constant body weight, the sum of testicular and epididymal androgen-binding protein was identical in both normo- and hyperglycaemic animals. This disturbance in androgen-binding protein distribution may be the consequence of altered testicular secretion or impaired transport of androgen-binding protein from testes to epididymides.
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April 1973,
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Steroids,
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Endocrinology,
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Vitamins and hormones,
N Kühn-Velten, and
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April 1984,
Endocrinology,
N Kühn-Velten, and
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Journal of reproduction and fertility,
N Kühn-Velten, and
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Nihon Naibunpi Gakkai zasshi,
N Kühn-Velten, and
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September 1977,
Fertility and sterility,
N Kühn-Velten, and
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Endocrinology,
