Biomaterial Database

Effect of lesion location within the medial preoptic-anterior hypothalamic continuum on maternal and male sexual behaviors in female rats. 1984

P Gray, and P J Brooks

Lesions of the medial preoptic-anterior hypothalamic continuum (MPOA-AH) are known to disrupt both maternal behavior and male sexual behavior in the rat. In order to test the hypothesis that the two behaviors involve different neural systems in the MPOA-AH, small bilateral lesions were made in different anterior-posterior locations in the MPOA-AH of maternal-sensitized, testosterone-treated female rats, and the effects of these lesions on maternal and male sexual behaviors were assessed. Lesions centering in the MPOA disrupted maternal behavior (pup retrieval, nest building, and nursing), with anterior MPOA lesions being more effective (on pup retrieval and nest building) than posterior MPOA lesions. Lesions centering in the AH had little or no effect on maternal behavior. By contrast, male sexual behavior (mounting) was strongly disrupted by lesions in either the MPOA or the AH, with lesions in the rostral AH being most effective.

UI	MeSH Term	Description	Entries
D007032	Hypothalamus, Anterior	The front portion of the HYPOTHALAMUS separated into the preoptic region and the supraoptic region. The preoptic region is made up of the periventricular GRAY MATTER of the rostral portion of the THIRD VENTRICLE and contains the preoptic ventricular nucleus and the medial preoptic nucleus. The supraoptic region contains the PARAVENTRICULAR HYPOTHALAMIC NUCLEUS, the SUPRAOPTIC NUCLEUS, the ANTERIOR HYPOTHALAMIC NUCLEUS, and the SUPRACHIASMATIC NUCLEUS.	Hypothalamus, Supraoptic,Anterior Hypothalamic Commissure,Anterior Hypothalamic Decussation of Ganser,Anteroventral Periventricular Nucleus,Anterior Hypothalamic Commissures,Anterior Hypothalamus,Commissure, Anterior Hypothalamic,Commissures, Anterior Hypothalamic,Hypothalamic Commissure, Anterior,Hypothalamic Commissures, Anterior,Nucleus, Anteroventral Periventricular,Periventricular Nucleus, Anteroventral,Supraoptic Hypothalamus
D007062	Identification, Psychological	A process by which an individual unconsciously endeavors to pattern himself after another. This process is also important in the development of the personality, particularly the superego or conscience, which is modeled largely on the behavior of adult significant others.	Identification (Psychology),Identification, Psychology,Identifications (Psychology),Identifications, Psychological,Identifications, Psychology,Psychological Identification,Psychological Identifications,Psychology Identification,Psychology Identifications
D008425	Maternal Behavior	The behavior patterns associated with or characteristic of a mother.	Maternal Patterns of Care,Maternal Care Patterns,Behavior, Maternal,Behaviors, Maternal,Care Pattern, Maternal,Care Patterns, Maternal,Maternal Behaviors,Maternal Care Pattern,Pattern, Maternal Care,Patterns, Maternal Care
D011301	Preoptic Area	Region of hypothalamus between the ANTERIOR COMMISSURE and OPTIC CHIASM.	Area Preoptica,Lateral Preoptic Area,Medial Preoptic Area,Preoptic Nuclei,Area Preopticas,Area, Lateral Preoptic,Area, Medial Preoptic,Area, Preoptic,Areas, Lateral Preoptic,Areas, Medial Preoptic,Areas, Preoptic,Lateral Preoptic Areas,Medial Preoptic Areas,Nuclei, Preoptic,Nucleus, Preoptic,Preoptic Area, Lateral,Preoptic Area, Medial,Preoptic Areas,Preoptic Areas, Lateral,Preoptic Areas, Medial,Preoptic Nucleus,Preoptica, Area,Preopticas, Area
D001931	Brain Mapping	Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.	Brain Electrical Activity Mapping,Functional Cerebral Localization,Topographic Brain Mapping,Brain Mapping, Topographic,Functional Cerebral Localizations,Mapping, Brain,Mapping, Topographic Brain
D005260	Female		Females
D005783	Gender Identity	A person's concept of self as being male and masculine or female and feminine, or ambivalent, based in part on physical characteristics, parental responses, and psychological and social pressures. It is the internal experience of gender role.	Gender,Gender Identities,Identity, Gender
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012726	Sexual Behavior, Animal	Sexual activities of animals.	Mating Behavior, Animal,Sex Behavior, Animal,Animal Mating Behavior,Animal Mating Behaviors,Animal Sex Behavior,Animal Sex Behaviors,Animal Sexual Behavior,Animal Sexual Behaviors,Mating Behaviors, Animal,Sex Behaviors, Animal,Sexual Behaviors, Animal