Forefoot capillary filtration rate measured during lowering in normal subjects and in patients with occlusive arterial disease before and after arterial reconstruction. 1984

J H Eickhoff

Capillary filtration rate (CFR) was measured by a mercury-in-silastic strain-gauge around the forefoot when the forefoot was lowered 40 cm below heart level. In seven normal limbs, CFR was 0.061 (0.049-0.086) ml (100 g min)-1 against 0.049 (0.016-0.071) ml (100 g min)-1 in 24 limbs with occlusive arterial disease (P = 0.01). About 8 days after arterial reconstruction CFR decreased to 0.039 (0.018-0.071) ml (100 g min)-1, but before 3 months after reconstruction CFR increased to normal values 0.061 (0.037-0.071) ml (100 g min)-1. The explanation offered for the reduced CFR before and immediately after arterial reconstruction is temporary thrombosis in the smallest distributing arteries and in the arterioles resulting in heterogeneous flow distribution and decreased fluid filtration in poorly perfused segments of the capillary bed. The results speak against increased capillary filtration as the aetiology of the post-reconstructive oedema.

UI MeSH Term Description Entries
D007383 Intermittent Claudication A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE. Claudication, Intermittent
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D011187 Posture The position or physical attitude of the body. Postures
D001794 Blood Pressure PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS. Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D002199 Capillary Permeability The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement. Microvascular Permeability,Permeability, Capillary,Permeability, Microvascular,Vascular Permeability,Capillary Permeabilities,Microvascular Permeabilities,Permeabilities, Capillary,Permeabilities, Microvascular,Permeabilities, Vascular,Permeability, Vascular,Vascular Permeabilities
D004487 Edema Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE. Dropsy,Hydrops,Anasarca
D005260 Female Females
D005528 Foot The distal extremity of the leg in vertebrates, consisting of the tarsus (ANKLE); METATARSUS; phalanges; and the soft tissues surrounding these bones. Feet

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