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Counterimmunoelectrophoresis (C.I.E.) is suitable for routine-work in clinical medicine to give quantitative evidence of precipitating antibodies. Sensitivity of this method is high (lowest level being 200 to 400 ng albumin/ml serum) and range of evidence being very broad (14-15 titer steps). The direction of migrations of proteins with anodal migration (Ig) is changed by carbamylation. The experience gained in more than 3,000 investigations, concerning methods and evaluation of the results, is reported in detail. Counterimmunoelectrophoresis is superior to immunoelectrophoresis and double diffusion (Ouchterlony) due to its higher sensitivity and to RAST or RIST by reason of its lower costs.
P Luther, and
K C Bergmann
August 1980,
Nihon Kyobu Shikkan Gakkai zasshi,
P Luther, and
K C Bergmann
July 1976,
The American review of respiratory disease,
P Luther, and
K C Bergmann
June 1978,
Dermatologische Monatschrift,
P Luther, and
K C Bergmann
September 1986,
Boletin de la Oficina Sanitaria Panamericana. Pan American Sanitary Bureau,
P Luther, and
K C Bergmann
January 1994,
Mycoses,
P Luther, and
K C Bergmann
October 1973,
Chest,
P Luther, and
K C Bergmann
February 1982,
Nihon Kyobu Shikkan Gakkai zasshi,
P Luther, and
K C Bergmann
June 1974,
Annales d'immunologie,
P Luther, and
K C Bergmann
January 1984,
Revista do Instituto de Medicina Tropical de Sao Paulo,
P Luther, and
K C Bergmann
February 1976,
European journal of pediatrics,
