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Parental age and incidence of cleft lip and cleft palate anomalies. 1984

R S Balgir

Maternal and paternal age effects have been studied on 90 patients (61 males and 29 females) suffering from cleft lip, cleft palate and, cleft lip and palate anomalies. Younger mothers are at higher risk of getting a child with congenital oral clefts than the older (above 30 years of age). Parental age gaps increase the incidence of congenital malformations.

UI MeSH Term Description Entries
D008297 Male Males
D008423 Maternal Age The age of the mother in PREGNANCY. Age, Maternal,Ages, Maternal,Maternal Ages
D010331 Paternal Age Age of the biological father. Age, Paternal,Ages, Paternal,Paternal Ages
D002971 Cleft Lip Congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences. It is thought to be caused by faulty migration of the mesoderm in the head region. Harelip,Cleft Lips,Harelips,Lip, Cleft,Lips, Cleft
D002972 Cleft Palate Congenital fissure of the soft and/or hard palate, due to faulty fusion. Cleft Palate, Isolated,Cleft Palates,Palate, Cleft,Palates, Cleft
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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