Biomaterial Database

Renal function in idiopathic respiratory distress syndrome. 1978

U Broberger, and A Aperia

Renal function was studied in 11 pre-term infants with idiopathic respiratory distress syndrome (IRDS) grade 1 according to Prod'hom's criteria. As a reference 16 healthy pre-term infants were studied. The groups did not differ with regard to mean gestational age (GA) and mean postnatal age (PNA). The studies were prefomred twice, first at a PNA of 33--37 hours and then at 132--148 hours. GFR and CPAH were determined with the single injection technique and the ability to excrete Na+ was determined following an oral Na+ load. GFR was higher in IRDS infants at the first investigation and slightly lower in IRDS infants at the second investigation. The GFR correlated to the lowest recorded PaO2 (r=0.45) in IRDS infants. CPAH was similar in IRDS and controls at the first, and lower in IRDS infants at the second investigation. The urinary Na+ excretion was significantly higher in IRDS infants. Treatment with digitalis was in part responsible for the high urinary Na+ excretion. The IRDS infants had a higher Na+ and glucose intake than the control infants. It is suggested that this higher intake is in part responsible for the relatively high GFR and urinary Na+ excretion in IRDS infants.

UI	MeSH Term	Description	Entries
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007444	Inulin	A starch found in the tubers and roots of many plants. Since it is hydrolyzable to FRUCTOSE, it is classified as a fructosan. It has been used in physiologic investigation for determination of the rate of glomerular function.
D007668	Kidney	Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.	Kidneys
D007677	Kidney Function Tests	Laboratory tests used to evaluate how well the kidneys are working through examination of blood and urine.	Function Test, Kidney,Function Tests, Kidney,Kidney Function Test,Test, Kidney Function,Tests, Kidney Function
D008297	Male		Males
D009318	Natriuresis	Sodium excretion by URINATION.	Natriureses
D010130	p-Aminohippuric Acid	The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.	4-Aminohippuric Acid,para-Aminohippuric Acid,Aminohippurate Sodium,Aminohippuric Acid,Nephrotest,Sodium Para-Aminohippurate,p-Aminohippurate,4 Aminohippuric Acid,Para-Aminohippurate, Sodium,Sodium Para Aminohippurate,Sodium, Aminohippurate,p Aminohippurate,p Aminohippuric Acid,para Aminohippuric Acid
D010313	Partial Pressure	The pressure that would be exerted by one component of a mixture of gases if it were present alone in a container. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Partial Pressures,Pressure, Partial,Pressures, Partial
D012127	Respiratory Distress Syndrome, Newborn	A condition of the newborn marked by DYSPNEA with CYANOSIS, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause.	Infantile Respiratory Distress Syndrome,Neonatal Respiratory Distress Syndrome,Respiratory Distress Syndrome, Infant
D001794	Blood Pressure	PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.	Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic