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In a blind, randomized study, the effect of breathing 100 p.p.m. of CO versus compressed, purified air for 2 hours on ventricular fibrillation threshold (VFT) was investigated in 21 dogs with acute myocardial injury. The mean arterial carboxyhemoglobin was 1.16 per cent in the air control period, 1.07 per cent after air, 1.08 per cent in the CO control period, and 6.34 per cent after CO. In comparison to air, CO increased the mean arterial carboxyhemoglobin (P less than 0.001). One dog developed spontaneous ventricular fibrillation 100 minutes after CO. Mean VFTs in the other 20 dogs were 12.8 +/- 6.8 milliamperes after CO, 11.2 +/- 6.0 milliamperes in the air control period, and 15.0 +/- 5.1 milliamperes after air. In comparison to air, CO decreased the VFT (P less than 0.001). These data show that breathing 100 p.p.m. of CO for 2 hours reduces the VFT in dogs with acute myocardial injury.
W S Aronow, and
E A Stemmer, and
B Wood, and
S Zweig, and
K P Tsao, and
L Raggio
August 1972,
American heart journal,
W S Aronow, and
E A Stemmer, and
B Wood, and
S Zweig, and
K P Tsao, and
L Raggio
January 1972,
American heart journal,
W S Aronow, and
E A Stemmer, and
B Wood, and
S Zweig, and
K P Tsao, and
L Raggio
June 1968,
Thoraxchirurgie, vaskulare Chirurgie,
W S Aronow, and
E A Stemmer, and
B Wood, and
S Zweig, and
K P Tsao, and
L Raggio
June 1968,
Zeitschrift fur Tropenmedizin und Parasitologie,
W S Aronow, and
E A Stemmer, and
B Wood, and
S Zweig, and
K P Tsao, and
L Raggio
December 2012,
Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology,
W S Aronow, and
E A Stemmer, and
B Wood, and
S Zweig, and
K P Tsao, and
L Raggio
January 1973,
Cardiology,
W S Aronow, and
E A Stemmer, and
B Wood, and
S Zweig, and
K P Tsao, and
L Raggio
June 1982,
American heart journal,
W S Aronow, and
E A Stemmer, and
B Wood, and
S Zweig, and
K P Tsao, and
L Raggio
July 1975,
Cardiovascular research,
W S Aronow, and
E A Stemmer, and
B Wood, and
S Zweig, and
K P Tsao, and
L Raggio
April 2009,
Giornale italiano di cardiologia (2006),
W S Aronow, and
E A Stemmer, and
B Wood, and
S Zweig, and
K P Tsao, and
L Raggio
April 1980,
Canadian journal of physiology and pharmacology,
