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The effect of chronic beta-adrenergic stimulation with isoproterenol on the kallikrein content of rat submandibular gland was estimated by radioimmunoassay, by immunohistochemistry, and by analytical isoelectric focusing. Radioimmunoassays revealed that the kallikrein content of the submandibular gland was already significantly decreased after 6 days of treatment. After 21 days, the kallikrein content was 40 times lower and by 33 days an almost complete depletion was found. These findings were confirmed by immunohistochemistry. Analytical isoelectric focusing also showed that, after 33 days of treatment, the typical bands corresponding to the kallikrein isoenzymes of the submandibular gland had disappeared. These results indicate that kallikrein secretion is influenced by beta-adrenergic stimulation.
J Gutkowska, and
G Thibault, and
M Cantin, and
R Garcia, and
J Genest
June 1982,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
J Gutkowska, and
G Thibault, and
M Cantin, and
R Garcia, and
J Genest
January 1976,
Experimental gerontology,
J Gutkowska, and
G Thibault, and
M Cantin, and
R Garcia, and
J Genest
January 1994,
Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie,
J Gutkowska, and
G Thibault, and
M Cantin, and
R Garcia, and
J Genest
December 1973,
The American journal of anatomy,
J Gutkowska, and
G Thibault, and
M Cantin, and
R Garcia, and
J Genest
June 1995,
Microscopy research and technique,
J Gutkowska, and
G Thibault, and
M Cantin, and
R Garcia, and
J Genest
January 1992,
Archives of oral biology,
J Gutkowska, and
G Thibault, and
M Cantin, and
R Garcia, and
J Genest
May 1981,
Chemical & pharmaceutical bulletin,
J Gutkowska, and
G Thibault, and
M Cantin, and
R Garcia, and
J Genest
February 1981,
The Journal of pharmacology and experimental therapeutics,
J Gutkowska, and
G Thibault, and
M Cantin, and
R Garcia, and
J Genest
October 1980,
Canadian journal of physiology and pharmacology,
J Gutkowska, and
G Thibault, and
M Cantin, and
R Garcia, and
J Genest
August 1993,
Mechanisms of ageing and development,
