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The total daily amount of extractable cationic trypsin, chymotrypsin, and pancreatic elastase 2 in feces and ileostomy fluids has been studied in normal individuals and healthy colectomized subjects. Quantitation was performed using immunological assays with polyethylene glycol as a fecal marker. The extractable amount of each of these enzymes in the feces of normal individuals was less than 1 mg/24 h. However, in fecal extracts from antibiotic-treated normal individuals a 100-fold increase in immunoreactive cationic trypsin was observed, while chymotrypsin and elastase 2 were only 2- to 3-fold higher. In extracts from ileostomy fluids cationic trypsin, elastase, and chymotrypsin all showed mean values in the order of 50-200 mg/24 h. The characterization of the immunoreactivity of pancreatic proteases showed no qualitative differences when measured in duodenal juice or fecal and ileostomy extracts.
M Bohe, and
A Borgström, and
S Genell, and
K Ohlsson
January 1968,
Journal de pharmacie de Belgique,
M Bohe, and
A Borgström, and
S Genell, and
K Ohlsson
April 1989,
Clinical biochemistry,
M Bohe, and
A Borgström, and
S Genell, and
K Ohlsson
May 1976,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
M Bohe, and
A Borgström, and
S Genell, and
K Ohlsson
January 1986,
Acta obstetricia et gynecologica Scandinavica,
M Bohe, and
A Borgström, and
S Genell, and
K Ohlsson
January 1987,
Acta paediatrica Scandinavica,
M Bohe, and
A Borgström, and
S Genell, and
K Ohlsson
November 1990,
Pancreas,
M Bohe, and
A Borgström, and
S Genell, and
K Ohlsson
October 1984,
Deutsche medizinische Wochenschrift (1946),
M Bohe, and
A Borgström, and
S Genell, and
K Ohlsson
September 1980,
European journal of biochemistry,
M Bohe, and
A Borgström, and
S Genell, and
K Ohlsson
September 1981,
Acta paediatrica Scandinavica,
M Bohe, and
A Borgström, and
S Genell, and
K Ohlsson
July 1978,
Biochimica et biophysica acta,
