Standardized stress and hypertension: comparison of effect of propranolol and methyldopa. 1978

F G Dunn, and D I Melville, and J V Jones, and A R Lorimer, and T D Lawrie

1 Using a standardized form of mental stress, 21 patients with idiopathic hypertension were investigated before and after treatment with placebo (n=8), propranolol (n=7) or methyldopa (n=6). 2 Blood pressure was satisfactorily controlled in the propranolol and methyldopa groups but only the propranolol group showed modification of the pressor response to stress testing. 3 These results suggest that propranolol may provide more uniform control of blood pressure than methyldopa in patients with essential hypertension.

UI MeSH Term Description Entries
D006973 Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. Blood Pressure, High,Blood Pressures, High,High Blood Pressure,High Blood Pressures
D008297 Male Males
D008750 Methyldopa An alpha-2 adrenergic agonist that has both central and peripheral nervous system effects. Its primary clinical use is as an antihypertensive agent. Methyldopate,alpha-Methyldopa,Aldomet,Alphamethyldopa,Apo-Methyldopa,Dopamet,Dopegit,Dopegyt,Dopergit,Hydopa,Meldopa,Nu-Medopa,Sembrina,alpha-Methyl-L-Dopa,Apo Methyldopa,Nu Medopa,alpha Methyl L Dopa,alpha Methyldopa
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011433 Propranolol A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs. Dexpropranolol,AY-20694,Anaprilin,Anapriline,Avlocardyl,Betadren,Dociton,Inderal,Obsidan,Obzidan,Propanolol,Propranolol Hydrochloride,Rexigen,AY 20694,AY20694,Hydrochloride, Propranolol
D001794 Blood Pressure PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS. Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013312 Stress, Physiological The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions. Biotic Stress,Metabolic Stress,Physiological Stress,Abiotic Stress,Abiotic Stress Reaction,Abiotic Stress Response,Biological Stress,Metabolic Stress Response,Physiological Stress Reaction,Physiological Stress Reactivity,Physiological Stress Response,Abiotic Stress Reactions,Abiotic Stress Responses,Abiotic Stresses,Biological Stresses,Biotic Stresses,Metabolic Stress Responses,Metabolic Stresses,Physiological Stress Reactions,Physiological Stress Responses,Physiological Stresses,Reaction, Abiotic Stress,Reactions, Abiotic Stress,Response, Abiotic Stress,Response, Metabolic Stress,Stress Reaction, Physiological,Stress Response, Metabolic,Stress Response, Physiological,Stress, Abiotic,Stress, Biological,Stress, Biotic,Stress, Metabolic

Related Publications

F G Dunn, and D I Melville, and J V Jones, and A R Lorimer, and T D Lawrie
January 1980, Indian heart journal,
F G Dunn, and D I Melville, and J V Jones, and A R Lorimer, and T D Lawrie
January 1976, Advances in clinical pharmacology,
F G Dunn, and D I Melville, and J V Jones, and A R Lorimer, and T D Lawrie
July 1976, British medical journal,
F G Dunn, and D I Melville, and J V Jones, and A R Lorimer, and T D Lawrie
December 1976, Clinical science and molecular medicine. Supplement,
F G Dunn, and D I Melville, and J V Jones, and A R Lorimer, and T D Lawrie
May 1973, Ugeskrift for laeger,
F G Dunn, and D I Melville, and J V Jones, and A R Lorimer, and T D Lawrie
May 1976, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
F G Dunn, and D I Melville, and J V Jones, and A R Lorimer, and T D Lawrie
October 1977, Clinical pharmacology and therapeutics,
F G Dunn, and D I Melville, and J V Jones, and A R Lorimer, and T D Lawrie
September 1984, The Journal of the Association of Physicians of India,
F G Dunn, and D I Melville, and J V Jones, and A R Lorimer, and T D Lawrie
October 1984, Journal of clinical pharmacology,
F G Dunn, and D I Melville, and J V Jones, and A R Lorimer, and T D Lawrie
February 1976, Annals of clinical research,
Copied contents to your clipboard!