-transparent.png){kind=logo}
6 patients with end-stage renal disease underwent hemoperfusion with charcoal columns, for 60 min. Blood samples anticoagulated with 2% EDTA/aspirin solution were obtained from arteriovenous fistulas in the basal condition, 5 min after a bolus injection of heparin (7,500 U), at the end of hemoperfusion, and 30 min after. The study was repeated few days later, in the same patients, two hours after 100 mg aspirin by mouth. TXB2 and 6-keto-PGF1 alpha were assayed with RIA in unextracted (U) and extracted (E) and chromatographed platelet poor plasma (PPP). Platelet counts before and after hemoperfusion were also performed. Low levels of the two prostaglandins were found in plasma; this could be related to the procedures for collection and processing of plasma samples; no significant differences were observed between extracted and unextracted samples: there were slightly higher levels of 6-keto-PGF1 alpha in unextracted samples. After charcoal hemoperfusion there was only a slight and not significant increase of TXB2 and 6-keto-PGF1 alpha; low dose aspirin did not modify significantly plasma levels of the two prostaglandins before hemoperfusion but it reduced TXB2 and 6-keto-PGF1 alpha levels after charcoal hemoperfusion. The platelet count fell (-22%) after charcoal hemoperfusion with heparin alone and in similar manner after low-dose aspirin pretreatment (-24%, 7%).
G Davì, and
M Orlandi, and
F Picone, and
G Galione, and
C Meringolo, and
A Mazzola, and
V Tomasi, and
G Capodicasa, and
A Strano
March 1992,
Thrombosis research,
G Davì, and
M Orlandi, and
F Picone, and
G Galione, and
C Meringolo, and
A Mazzola, and
V Tomasi, and
G Capodicasa, and
A Strano
September 1988,
Arerugi = [Allergy],
G Davì, and
M Orlandi, and
F Picone, and
G Galione, and
C Meringolo, and
A Mazzola, and
V Tomasi, and
G Capodicasa, and
A Strano
December 1998,
Yao xue xue bao = Acta pharmaceutica Sinica,
G Davì, and
M Orlandi, and
F Picone, and
G Galione, and
C Meringolo, and
A Mazzola, and
V Tomasi, and
G Capodicasa, and
A Strano
February 1986,
Masui. The Japanese journal of anesthesiology,
G Davì, and
M Orlandi, and
F Picone, and
G Galione, and
C Meringolo, and
A Mazzola, and
V Tomasi, and
G Capodicasa, and
A Strano
February 1994,
The Journal of the Association of Physicians of India,
G Davì, and
M Orlandi, and
F Picone, and
G Galione, and
C Meringolo, and
A Mazzola, and
V Tomasi, and
G Capodicasa, and
A Strano
March 1999,
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan,
G Davì, and
M Orlandi, and
F Picone, and
G Galione, and
C Meringolo, and
A Mazzola, and
V Tomasi, and
G Capodicasa, and
A Strano
January 1987,
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao,
G Davì, and
M Orlandi, and
F Picone, and
G Galione, and
C Meringolo, and
A Mazzola, and
V Tomasi, and
G Capodicasa, and
A Strano
December 1989,
Zhonghua xin xue guan bing za zhi,
G Davì, and
M Orlandi, and
F Picone, and
G Galione, and
C Meringolo, and
A Mazzola, and
V Tomasi, and
G Capodicasa, and
A Strano
January 1989,
Zhonghua nei ke za zhi,
G Davì, and
M Orlandi, and
F Picone, and
G Galione, and
C Meringolo, and
A Mazzola, and
V Tomasi, and
G Capodicasa, and
A Strano
November 1993,
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology,
