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In previous publications (Jones et al., 1977; Nordin et al., 1980) we have shown that menopausal symptoms respond well to 15 micrograms of ethinyl oestradiol and rather less well to 5 mg daily of norethisterone. We have not previously established whether even smaller doses of ethinyl oestradiol might be effective or whether combining this preparation with norethisterone might produce an additive effect. The present paper describes a trial designed to answer these questions.
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