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A 13-month-old female with middle and upper lobe pneumonia showed a high WBC count with 99% blasts. From hematologic studies the condition was diagnosed as acute myelocytic leukemia (AML). In spite of aggressive chemotherapy, the patient died. Unstimulated peripheral blood culture and bone marrow cells revealed a translocation between a chromosome #2 and #6. An interstitial segment of 2q had been translocated to 6p. A chromosome #22 was also abnormal, having acquired a dark band around the long arm.
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