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The aim of the present report was to study the course of development of rat Leydig cells from 17 fetal day (f.d.) up to 5 postnatal day (p.n.d.), with the help of enzymhistochemical reaction of delta 5-3 beta Hydroxysteroid-dehydrogenase (3 beta-HSDH). Testes were obtained from 17 to 21 days old embryos and from 1 to 5 days old offsprings. Cryostat sections were cut and processed for enzymhistochemical reaction of 3 beta-HSDH, employing dehydroepiandrosterone as substrate. The areas of the Leydig cells, showing the enzymatic activity, were measured morphometrically. The 3 beta-HSDH positive intertubular Leydig cells appear on 17 f.d., and grow further showing a maximum peak, relative to the size of the testis, on 19 f.d. Thereafter, the percentage of the Leydig cells relative to the size of the testis decreases continuously up to 4 p.n.d.. The Leydig cells did not regress during the period of observation. Postnatally, the large complexes disperse into many small complexes.
H G Ziegler, and
S G Haider, and
D Passia, and
W Hilscher
January 1986,
Acta histochemica. Supplementband,
H G Ziegler, and
S G Haider, and
D Passia, and
W Hilscher
December 1980,
Steroids,
H G Ziegler, and
S G Haider, and
D Passia, and
W Hilscher
February 1982,
International journal of andrology,
H G Ziegler, and
S G Haider, and
D Passia, and
W Hilscher
September 1984,
Endocrinologia experimentalis,
H G Ziegler, and
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D Passia, and
W Hilscher
June 1980,
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H G Ziegler, and
S G Haider, and
D Passia, and
W Hilscher
January 1985,
Indian journal of physiology and pharmacology,
H G Ziegler, and
S G Haider, and
D Passia, and
W Hilscher
January 1992,
Endocrinology,
H G Ziegler, and
S G Haider, and
D Passia, and
W Hilscher
October 1969,
Nihon Sanka Fujinka Gakkai zasshi,
H G Ziegler, and
S G Haider, and
D Passia, and
W Hilscher
April 1973,
Endocrinology,
H G Ziegler, and
S G Haider, and
D Passia, and
W Hilscher
March 1965,
Endocrinology,
