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Tumor forming acute promyelocytic leukemia (APL) is rare and only three cases have been documented. However, there are no reports on either the chloromatous character or electron microscopical analysis. The present paper dealt with a light, electron microscopic and histochemical study of the tumor of APL in a 55-year-old Japanese male. The tumors found in the anterior mediastinum and right lower extremity. He died from respiratory disturbance and hydrothorax due to obstruction of the pulmonary truncus by the mediastinal tumor. In electron microscopy, the tumor cells showed dilatation, colloracious pattern and honey-comb-like structure of rough endoplasmic reticula (RER) and parallel array-arrangement of smooth endoplasmic reticula (SER). These abnormalities of ER are the same as those recently recognized in leukemic cells in APL. Furthermore, the intercellular junctions composed of opposing dense patches of the cytoplasmic plasmalemma were frequently found between the more immature tumor cell of the mediastinum.
K Nihei, and
K Terashima, and
T Nito, and
Y Imai, and
K Aoyama, and
K Takahashi, and
H Ando, and
K Koike, and
H Sasaki
September 1969,
The Keio journal of medicine,
K Nihei, and
K Terashima, and
T Nito, and
Y Imai, and
K Aoyama, and
K Takahashi, and
H Ando, and
K Koike, and
H Sasaki
December 1981,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
K Nihei, and
K Terashima, and
T Nito, and
Y Imai, and
K Aoyama, and
K Takahashi, and
H Ando, and
K Koike, and
H Sasaki
January 1957,
Polski tygodnik lekarski,
K Nihei, and
K Terashima, and
T Nito, and
Y Imai, and
K Aoyama, and
K Takahashi, and
H Ando, and
K Koike, and
H Sasaki
December 1981,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
K Nihei, and
K Terashima, and
T Nito, and
Y Imai, and
K Aoyama, and
K Takahashi, and
H Ando, and
K Koike, and
H Sasaki
January 2008,
Vnitrni lekarstvi,
K Nihei, and
K Terashima, and
T Nito, and
Y Imai, and
K Aoyama, and
K Takahashi, and
H Ando, and
K Koike, and
H Sasaki
June 1978,
Klinische Wochenschrift,
K Nihei, and
K Terashima, and
T Nito, and
Y Imai, and
K Aoyama, and
K Takahashi, and
H Ando, and
K Koike, and
H Sasaki
October 1984,
Oral surgery, oral medicine, and oral pathology,
K Nihei, and
K Terashima, and
T Nito, and
Y Imai, and
K Aoyama, and
K Takahashi, and
H Ando, and
K Koike, and
H Sasaki
September 1976,
Seminars in oncology,
K Nihei, and
K Terashima, and
T Nito, and
Y Imai, and
K Aoyama, and
K Takahashi, and
H Ando, and
K Koike, and
H Sasaki
September 1955,
La Presse medicale,
K Nihei, and
K Terashima, and
T Nito, and
Y Imai, and
K Aoyama, and
K Takahashi, and
H Ando, and
K Koike, and
H Sasaki
July 1977,
Scandinavian journal of haematology,
