-transparent.png){kind=logo}
Twenty-four adolescent and adult patients with newly diagnosed acute lymphoblastic leukemia (ALL) were treated with the multidrug therapeutic program called IGG-74(9). Seventeen patients (71%) obtained a complete remission (CR) after induction therapy. They subsequently underwent a consolidation course with cytosine arabinoside and a seven drug maintenance regimen, lasting three years, with cyclophosphamide, 6 mercaptopurine, methotrexate, BCNU, adriamycin, vincristine and prednisone. The remission continuation treatment was well tolerated and produced an actuarial three-year disease-free survival rate of 57% and an overall median survival of 19 months. The efficacy of multidrug programs for the prevention of relapse in adults with ALL is discussed.
G Rossi, and
P Verzura, and
P Marpicati, and
A Zaniboni, and
P Ferremi, and
G Marini, and
G Marinone
February 1990,
Sangre,
G Rossi, and
P Verzura, and
P Marpicati, and
A Zaniboni, and
P Ferremi, and
G Marini, and
G Marinone
January 1977,
Medical and pediatric oncology,
G Rossi, and
P Verzura, and
P Marpicati, and
A Zaniboni, and
P Ferremi, and
G Marini, and
G Marinone
March 1993,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
G Rossi, and
P Verzura, and
P Marpicati, and
A Zaniboni, and
P Ferremi, and
G Marini, and
G Marinone
February 1997,
Hematological oncology,
G Rossi, and
P Verzura, and
P Marpicati, and
A Zaniboni, and
P Ferremi, and
G Marini, and
G Marinone
January 1987,
Haematology and blood transfusion,
G Rossi, and
P Verzura, and
P Marpicati, and
A Zaniboni, and
P Ferremi, and
G Marini, and
G Marinone
January 1989,
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
G Rossi, and
P Verzura, and
P Marpicati, and
A Zaniboni, and
P Ferremi, and
G Marini, and
G Marinone
July 1991,
Seminars in hematology,
G Rossi, and
P Verzura, and
P Marpicati, and
A Zaniboni, and
P Ferremi, and
G Marini, and
G Marinone
April 1987,
Blood,
G Rossi, and
P Verzura, and
P Marpicati, and
A Zaniboni, and
P Ferremi, and
G Marini, and
G Marinone
November 1987,
Anales espanoles de pediatria,
G Rossi, and
P Verzura, and
P Marpicati, and
A Zaniboni, and
P Ferremi, and
G Marini, and
G Marinone
December 1993,
Seminars in oncology,
