Biomaterial Database

Compartmental pressure measurements during application of the pneumatic antishock garment. 1984

J R Hedges, and P B Baker, and W C Dalsey

Department of Emergency Medicine, University of Cincinnati Medical Center, Ohio 45267.

Recent case reports have implicated the pneumatic antishock garment (PASG) in the development of the compartment syndrome in the lower extremities. The present study used the anterolateral compartment of the canine hindlimb to model the effect of the PASG on tissue pressure within the compartment (Pc). Prior to inflation of the garment, baseline Pc was 5.3 mm Hg. PASG inflation to 60 mm Hg for 20 minutes resulted in an increase in Pc of 75.0 mm Hg over baseline values. The rise in Pc was reduced significantly following hemorrhage of the animal, measuring 65.8 mm Hg at a mean arterial pressure of 70 to 80 mm Hg and 62.5 mm Hg at a mean arterial pressure of 40 to 50 mm Hg. In the immediate postarrest state, Pc rise after a five-minute inflation of the garment was 57.5 mm Hg. In all cases, Pc promptly returned to baseline values when the PASG was deflated, and there was no significant change in Pc following deflation of the garment under conditions of normotension, hemorrhagic hypotension, and in the immediate postarrest state. Our results suggest that the level of arterial pressure may contribute to Pc rise during PASG inflation.

UI	MeSH Term	Description	Entries
D007022	Hypotension	Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.	Blood Pressure, Low,Hypotension, Vascular,Low Blood Pressure,Vascular Hypotension
D007511	Ischemia	A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.	Ischemias
D011312	Pressure	A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Pressures
D001794	Blood Pressure	PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.	Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D003161	Compartment Syndromes	Conditions in which increased pressure within a limited space compromises the BLOOD CIRCULATION and function of tissue within that space. Some of the causes of increased pressure are TRAUMA, tight dressings, HEMORRHAGE, and exercise. Sequelae include nerve compression (NERVE COMPRESSION SYNDROMES); PARALYSIS; and ISCHEMIC CONTRACTURE. FASCIOTOMY is often used to decompress increased pressure and eliminate pain associated with compartment syndromes.	Compartment Syndrome
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D005676	Gravity Suits	Double-layered inflatable suits which, when inflated, exert pressure on the lower part of the wearer's body. The suits are used to improve or stabilize the circulatory state, i.e., to prevent hypotension, control hemorrhage, and regulate blood pressure. The suits are also used by pilots under positive acceleration.	Anti-Shock Trousers,Antigravity Suits,MAST Suit,Medical Anti-Shock Trousers,Military Anti-Shock Trousers,Pneumatic Suits,Pressure Suits,Antishock Trousers,Military Antishock Trousers,Anti Shock Trousers,Anti-Shock Trouser, Medical,Anti-Shock Trousers, Medical,Anti-Shock Trousers, Military,Antishock Trousers, Military,Gravity Suit,MAST Suits,Medical Anti Shock Trousers,Medical Anti-Shock Trouser,Military Anti Shock Trousers,Pneumatic Suit,Pressure Suit,Suit, Antigravity,Suit, Gravity,Suit, MAST,Suit, Pneumatic,Suit, Pressure,Suits, Antigravity,Trouser, Medical Anti-Shock,Trousers, Anti-Shock,Trousers, Antishock,Trousers, Medical Anti-Shock,Trousers, Military Anti-Shock,Trousers, Military Antishock
D006470	Hemorrhage	Bleeding or escape of blood from a vessel.	Bleeding,Hemorrhages
D006614	Hindlimb	Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)	Hindlimbs
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia