-transparent.png){kind=logo}
The clinical, hematological and pathological features of the adult T-cell leukemia (ATL)-related diseases and their cell membrane phenotypes in the Nagasaki district, one of the ATL-endemic areas, were delineated to compare them with those of adult T-cell leukemia-lymphoma (ATLL). In addition, the participation of ATL virus (ATLV) in the ATL-related diseases was investigated on the basis of a study of ATLV-associated antigen (ATLA) and anti-ATLA antibody. ATLA and/or anti-ATLA antibody could be detected in the ATL-related diseases, including persistent T-lymphocytosis with morphologically abnormal T-lymphocytes, T-cell chronic lymphocytic leukemia (T-CLL) of helper T-cells, T-cell malignant lymphoma of the skin, some seronegative helper T-cell malignant lymphomas and monomorphic T-cell leukemia with round nuclei. These results suggest that those cases in the Nagasaki district, though clinically different from each other, might be the same T-lymphoproliferative disease of possible viral etiology associated with ATLV. On the other hand, persistent T-lymphocytosis seems to be an infectious condition caused by ATLV and partly a preclinical stage of ATLL in view of the clinicohematological features.
K Kinoshita, and
T Amagasaki, and
Y Yamada, and
S Ikeda, and
S Momita, and
K Toriya, and
S Kamihira, and
M Ichimaru
March 1989,
International journal of dermatology,
K Kinoshita, and
T Amagasaki, and
Y Yamada, and
S Ikeda, and
S Momita, and
K Toriya, and
S Kamihira, and
M Ichimaru
March 1984,
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine,
K Kinoshita, and
T Amagasaki, and
Y Yamada, and
S Ikeda, and
S Momita, and
K Toriya, and
S Kamihira, and
M Ichimaru
April 2010,
Journal of medical virology,
K Kinoshita, and
T Amagasaki, and
Y Yamada, and
S Ikeda, and
S Momita, and
K Toriya, and
S Kamihira, and
M Ichimaru
November 1985,
[Hokkaido igaku zasshi] The Hokkaido journal of medical science,
K Kinoshita, and
T Amagasaki, and
Y Yamada, and
S Ikeda, and
S Momita, and
K Toriya, and
S Kamihira, and
M Ichimaru
April 2012,
Hematology (Amsterdam, Netherlands),
K Kinoshita, and
T Amagasaki, and
Y Yamada, and
S Ikeda, and
S Momita, and
K Toriya, and
S Kamihira, and
M Ichimaru
September 2004,
Frontiers in bioscience : a journal and virtual library,
K Kinoshita, and
T Amagasaki, and
Y Yamada, and
S Ikeda, and
S Momita, and
K Toriya, and
S Kamihira, and
M Ichimaru
July 2012,
The Gulf journal of oncology,
K Kinoshita, and
T Amagasaki, and
Y Yamada, and
S Ikeda, and
S Momita, and
K Toriya, and
S Kamihira, and
M Ichimaru
January 1998,
Ryoikibetsu shokogun shirizu,
K Kinoshita, and
T Amagasaki, and
Y Yamada, and
S Ikeda, and
S Momita, and
K Toriya, and
S Kamihira, and
M Ichimaru
August 2017,
Journal of oncology practice,
K Kinoshita, and
T Amagasaki, and
Y Yamada, and
S Ikeda, and
S Momita, and
K Toriya, and
S Kamihira, and
M Ichimaru
May 1989,
The Western journal of medicine,
