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Nineteen patients with severe aplastic anaemia were treated with antithymocyte globulin. Ten patients obtained remissions (transfusion independent, at least 45000 platelets and 2000 PMN/mm3) within 2-3 months and continue in remission 5-35 months after antithymocyte globulin. Ages of responders ranged from 17 to 71. Complications of antithymocyte globulin included arthralgias, rash, serum sickness, angioedema and fever. Two patients died during, two shortly after, and one 10 months after therapy. One patient with a previous remission following antithymocyte globulin relapsed and achieved a second remission with retreatment. Previous androgen therapy did not affect outcome since two of four patients with and eight of 15 patients without previous androgen therapy achieved remission with ATG. Treatment with antithymocyte globulin is a promising alternative to bone marrow transplantation in the treatment of severe aplastic anaemia.
W J Miller, and
R F Branda, and
P J Flynn, and
R B Howe, and
N K Ramsay, and
R M Condie, and
H S Jacob
October 1982,
Experimental hematology,
W J Miller, and
R F Branda, and
P J Flynn, and
R B Howe, and
N K Ramsay, and
R M Condie, and
H S Jacob
July 1983,
Lancet (London, England),
W J Miller, and
R F Branda, and
P J Flynn, and
R B Howe, and
N K Ramsay, and
R M Condie, and
H S Jacob
February 1997,
Bone marrow transplantation,
W J Miller, and
R F Branda, and
P J Flynn, and
R B Howe, and
N K Ramsay, and
R M Condie, and
H S Jacob
July 2021,
BMJ case reports,
W J Miller, and
R F Branda, and
P J Flynn, and
R B Howe, and
N K Ramsay, and
R M Condie, and
H S Jacob
July 2011,
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG,
W J Miller, and
R F Branda, and
P J Flynn, and
R B Howe, and
N K Ramsay, and
R M Condie, and
H S Jacob
June 2013,
Annals of hematology,
W J Miller, and
R F Branda, and
P J Flynn, and
R B Howe, and
N K Ramsay, and
R M Condie, and
H S Jacob
February 2014,
Pediatric hematology and oncology,
W J Miller, and
R F Branda, and
P J Flynn, and
R B Howe, and
N K Ramsay, and
R M Condie, and
H S Jacob
December 2006,
Leukemia research,
W J Miller, and
R F Branda, and
P J Flynn, and
R B Howe, and
N K Ramsay, and
R M Condie, and
H S Jacob
January 1985,
Acta haematologica,
W J Miller, and
R F Branda, and
P J Flynn, and
R B Howe, and
N K Ramsay, and
R M Condie, and
H S Jacob
January 1988,
The Journal of rheumatology,
