A date-independent predictor of intrauterine growth retardation: femur length/abdominal circumference ratio. 1983

F P Hadlock, and R L Deter, and R B Harrist, and E Roecker, and S K Park

The relation between sonographically measured fetal femur length and abdominal circumference (expressed as femur length/abdominal circumference X 100) was studied in 361 normal pregnancies between 15 and 42 weeks. This ratio was found to be independent of menstrual age, with a normal range after 21 weeks (mean +/- 2 SD) of 22 +/- 2. This ratio also was evaluated as a predictor of intrauterine growth retardation in 30 cases using the 90th percentile (23.5) as the upper limit of normal, which resulted in identification of 63% of the growth-retarded fetuses. Because it is independent of menstrual age, this ratio should prove most useful in evaluating high-risk patients who present in the third trimester of pregnancy with no dates. It is also of value in detecting growth retardation in patients with good menstrual history, since it was shown to become abnormal in asymmetrically growth-retarded fetuses before the estimated weight fell below the 10th percentile.

UI MeSH Term Description Entries
D008598 Menstruation The periodic shedding of the ENDOMETRIUM and associated menstrual bleeding in the MENSTRUAL CYCLE of humans and primates. Menstruation is due to the decline in circulating PROGESTERONE, and occurs at the late LUTEAL PHASE when LUTEOLYSIS of the CORPUS LUTEUM takes place.
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D005260 Female Females
D005269 Femur The longest and largest bone of the skeleton, it is situated between the hip and the knee. Trochanter,Greater Trochanter,Lesser Trochanter,Femurs,Greater Trochanters,Lesser Trochanters,Trochanter, Greater,Trochanter, Lesser,Trochanters,Trochanters, Greater,Trochanters, Lesser
D005317 Fetal Growth Retardation Failure of a FETUS to attain expected GROWTH. Growth Retardation, Intrauterine,Intrauterine Growth Retardation,Fetal Growth Restriction,Intrauterine Growth Restriction
D005865 Gestational Age The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated from the onset of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization. It is also estimated to begin from fertilization, estrus, coitus, or artificial insemination. Embryologic Age,Fetal Maturity, Chronologic,Chronologic Fetal Maturity,Fetal Age,Maturity, Chronologic Fetal,Age, Embryologic,Age, Fetal,Age, Gestational,Ages, Embryologic,Ages, Fetal,Ages, Gestational,Embryologic Ages,Fetal Ages,Gestational Ages
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000005 Abdomen That portion of the body that lies between the THORAX and the PELVIS. Abdomens
D012306 Risk The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome. Relative Risk,Relative Risks,Risk, Relative,Risks,Risks, Relative

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