Coronary bypass operation for early postinfarction angina. 1983

J E Molina, and J S Dorsey, and D A Emanuel, and J Reyes

A consecutive series of 38 patients who were hospitalized in the CCU for acute myocardial infarction and who had early postinfarction angina develop were operated upon on an emergency basis within two weeks after the initial infarction. The average time for the reapperance of angina was 1.7 days. Ten patients had reinfarction which occurred on an average of 3.2 days after the reappearance of the angina. Cardiogenic shock occurred in six patients between one to six days after the angina recurred. Three of these patients had severe mitral insufficiency that required mitral valve replacement in addition to the coronary bypass operation. Delay in evaluating these patients angiographically led to complications requiring the use of the intra-aortic balloon pump in 12 patients. The mean time for the angiographic evaluation was 6.8 days after the angina had recurred and the average time for surgical intervention was 1.2 days. The operative mortality in the patients undergoing coronary angiography and surgical treatment within 24 hours after the reappearance of angina (15 patients) was zero per cent; however, when this was delayed up to 48 hours (12 patients), the mortality increased to 8.3 per cent (one patient) and if the angiographic evaluation was delayed over 48 hours after the patient became symptomatic, the operative mortality rose substantially to 27.2 per cent (three patients). Most of the delay in obtaining angiocardiographic evaluation was caused by the attempt to use additional drug therapy or the introduction of new drugs, most of them calcium-blocking agents (nifedipine). It is our belief that physicians caring for patients who have recurrent angina after acute myocardial infarction should be aware that they represent a high risk group that should be studied angiographically promptly to determine operability in order to avoid a high rate of complications and death.

UI MeSH Term Description Entries
D007527 Isoenzymes Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics. Alloenzyme,Allozyme,Isoenzyme,Isozyme,Isozymes,Alloenzymes,Allozymes
D007770 L-Lactate Dehydrogenase A tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of LACTATE and PYRUVATE. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist. Lactate Dehydrogenase,Dehydrogenase, L-Lactate,Dehydrogenase, Lactate,L Lactate Dehydrogenase
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D008991 Monitoring, Physiologic The continuous measurement of physiological processes, blood pressure, heart rate, renal output, reflexes, respiration, etc., in a patient or experimental animal; includes pharmacologic monitoring, the measurement of administered drugs or their metabolites in the blood, tissues, or urine. Patient Monitoring,Monitoring, Physiological,Physiologic Monitoring,Monitoring, Patient,Physiological Monitoring
D009203 Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). Cardiovascular Stroke,Heart Attack,Myocardial Infarct,Cardiovascular Strokes,Heart Attacks,Infarct, Myocardial,Infarction, Myocardial,Infarctions, Myocardial,Infarcts, Myocardial,Myocardial Infarctions,Myocardial Infarcts,Stroke, Cardiovascular,Strokes, Cardiovascular
D012008 Recurrence The return of a sign, symptom, or disease after a remission. Recrudescence,Relapse,Recrudescences,Recurrences,Relapses
D003402 Creatine Kinase A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins. Creatine Phosphokinase,ADP Phosphocreatine Phosphotransferase,ATP Creatine Phosphotransferase,Macro-Creatine Kinase,Creatine Phosphotransferase, ATP,Kinase, Creatine,Macro Creatine Kinase,Phosphocreatine Phosphotransferase, ADP,Phosphokinase, Creatine,Phosphotransferase, ADP Phosphocreatine,Phosphotransferase, ATP Creatine
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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