BIOMAT Database Logo BIOMAT Database Logo

Human T-cell hybridomas secreting factors for B-cell differentiation and proliferation. 1983

S M Fu, and L Mayer, and H G Kunkel

UI MeSH Term Description Entries
D007136 Immunoglobulins Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses. Globulins, Immune,Immune Globulin,Immune Globulins,Immunoglobulin,Globulin, Immune
D002454 Cell Differentiation Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs. Differentiation, Cell,Cell Differentiations,Differentiations, Cell
D002455 Cell Division The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION. M Phase,Cell Division Phase,Cell Divisions,Division Phase, Cell,Division, Cell,Divisions, Cell,M Phases,Phase, Cell Division,Phase, M,Phases, M
D002460 Cell Line Established cell cultures that have the potential to propagate indefinitely. Cell Lines,Line, Cell,Lines, Cell
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006825 Hybridomas Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure MONOCLONAL ANTIBODIES or T-cell products, identical to those produced by the immunologically competent parent cell. Hybridoma
D001402 B-Lymphocytes Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation. B-Cells, Lymphocyte,B-Lymphocyte,Bursa-Dependent Lymphocytes,B Cells, Lymphocyte,B Lymphocyte,B Lymphocytes,B-Cell, Lymphocyte,Bursa Dependent Lymphocytes,Bursa-Dependent Lymphocyte,Lymphocyte B-Cell,Lymphocyte B-Cells,Lymphocyte, Bursa-Dependent,Lymphocytes, Bursa-Dependent
D013601 T-Lymphocytes Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen. T Cell,T Lymphocyte,T-Cells,Thymus-Dependent Lymphocytes,Cell, T,Cells, T,Lymphocyte, T,Lymphocyte, Thymus-Dependent,Lymphocytes, T,Lymphocytes, Thymus-Dependent,T Cells,T Lymphocytes,T-Cell,T-Lymphocyte,Thymus Dependent Lymphocytes,Thymus-Dependent Lymphocyte
D014066 Palatine Tonsil A round-to-oval mass of lymphoid tissue embedded in the lateral wall of the PHARYNX. There is one on each side of the oropharynx in the fauces between the anterior and posterior pillars of the SOFT PALATE. Tonsil,Tonsil, Palatine,Palatine Tonsils,Tonsils,Tonsils, Palatine

Related Publications

S M Fu, and L Mayer, and H G Kunkel
Human T cell hybridomas secreting immune interferon.
December 1982, Proceedings of the National Academy of Sciences of the United States of America,
S M Fu, and L Mayer, and H G Kunkel
B cell growth factors and B cell differentiation factor from human T hybridomas. Two distinct kinds of B cell growth factor and their synergism in B cell proliferation.
February 1983, The Journal of experimental medicine,
S M Fu, and L Mayer, and H G Kunkel
Development of a human T-cell hybridoma secreting separate B-cell growth and differentiation factors.
April 1984, Proceedings of the National Academy of Sciences of the United States of America,
S M Fu, and L Mayer, and H G Kunkel
Generation of stable human autoantibody-secreting B cell hybridomas.
May 1992, Molecular biology reports,
S M Fu, and L Mayer, and H G Kunkel
Human cell lines secreting lymphokines. I. Establishment of T-T hybridomas.
January 1987, Developments in biological standardization,
S M Fu, and L Mayer, and H G Kunkel
T-cell factors that promote B-cell proliferation and differentiation.
January 1985, Contemporary topics in molecular immunology,
S M Fu, and L Mayer, and H G Kunkel
Construction of T cell hybridomas secreting allogeneic effect factor.
October 1980, The Journal of experimental medicine,
S M Fu, and L Mayer, and H G Kunkel
UC 729-6, a human lymphoblastoid B-cell line useful for generating antibody-secreting human-human hybridomas.
October 1983, Proceedings of the National Academy of Sciences of the United States of America,
S M Fu, and L Mayer, and H G Kunkel
T-cell hybridomas which produce B lymphocyte replication factors only.
November 1982, Nature,
S M Fu, and L Mayer, and H G Kunkel
Growth and differentiation factors for B cells from human T cell clones.
January 1983, Lymphokine research,
Copied contents to your clipboard!