-transparent.png){kind=logo}
The mitotic index and number of abnormal metaphases of cells stimulated with the various B-cell polyclonal mitogens (PBA) in six B cell chronic lymphocytic leukemia (B-CLL) cases were evaluated. The PBA included tetradecanoyl-0-phorbol-13-acetate (TPA), staphylococcus bacterial strain Cowan I (Cowan I), pokeweed mitogen (PWM), Epstein-Barr virus (EBV), and lipopolysaccharide W from E. coli 0.55:B5 (LPS). TPA could stimulate only 1 of 12 samples. Even though Cowan I led to a relatively high mitotic index, abnormal clones were inconsistently obtained with this mitogen. PWM, EBV, and LPS appear to be the most desirable activators of B-CLL cells among the PBA used in this study.
N Sadamori, and
S Matsui, and
T Han, and
A A Sandberg
January 1985,
Haematologica,
N Sadamori, and
S Matsui, and
T Han, and
A A Sandberg
January 1988,
Medicina (Florence, Italy),
N Sadamori, and
S Matsui, and
T Han, and
A A Sandberg
June 2000,
Annals of hematology,
N Sadamori, and
S Matsui, and
T Han, and
A A Sandberg
October 1980,
Blood,
N Sadamori, and
S Matsui, and
T Han, and
A A Sandberg
November 2003,
Leukemia & lymphoma,
N Sadamori, and
S Matsui, and
T Han, and
A A Sandberg
March 2004,
Clinical lymphoma,
N Sadamori, and
S Matsui, and
T Han, and
A A Sandberg
January 1991,
Leukemia & lymphoma,
N Sadamori, and
S Matsui, and
T Han, and
A A Sandberg
August 2003,
Seminars in oncology,
N Sadamori, and
S Matsui, and
T Han, and
A A Sandberg
October 1987,
Seminars in hematology,
N Sadamori, and
S Matsui, and
T Han, and
A A Sandberg
September 1999,
Polskie Archiwum Medycyny Wewnetrznej,
