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Immunologic studies demonstrate that non-Hodgkin's lymphomas are derived predominantly from B- or T-lymphoid cells, while node-based tumors of true histiocytic derivation are rare, with few documented cases. This report describes the clinical, histologic, immunohistochemical, and ultrastructural features of two cases of node-based true histiocytic lymphoma. Distinctive ultrastructural features included numerous cytoplasmic lysosomes, surface microvillous processes, and occasional cell junctions, and the cells stained strongly for alpha-napthyl acetate esterase and alpha one-antitrypsin. Since there are few specific histologic features, special technics may be essential in confirming the diagnosis of true histiocytic lymphoma, and determining appropriate therapy.
P Thomas, and
J W Said, and
F P Rosenfelt, and
L J Heifetz
November 1998,
The American journal of surgical pathology,
P Thomas, and
J W Said, and
F P Rosenfelt, and
L J Heifetz
January 1984,
Histopathology,
P Thomas, and
J W Said, and
F P Rosenfelt, and
L J Heifetz
January 1981,
Virchows Archiv. A, Pathological anatomy and histology,
P Thomas, and
J W Said, and
F P Rosenfelt, and
L J Heifetz
January 1999,
Ultrastructural pathology,
P Thomas, and
J W Said, and
F P Rosenfelt, and
L J Heifetz
September 1985,
Histopathology,
P Thomas, and
J W Said, and
F P Rosenfelt, and
L J Heifetz
February 2004,
Journal of the American Academy of Dermatology,
P Thomas, and
J W Said, and
F P Rosenfelt, and
L J Heifetz
March 1999,
The British journal of dermatology,
P Thomas, and
J W Said, and
F P Rosenfelt, and
L J Heifetz
February 1991,
Seminars in oncology,
P Thomas, and
J W Said, and
F P Rosenfelt, and
L J Heifetz
August 1980,
Archives of dermatology,
P Thomas, and
J W Said, and
F P Rosenfelt, and
L J Heifetz
November 1983,
Cancer,
