Interleukin 2 (IL2) is assigned to human chromosome 4. 1984

T Shows, and R Eddy, and L Haley, and M Byers, and M Henry, and T Fujita, and H Matsui, and T Taniguchi

The human gene for interleukin 2 (IL2) was assigned to chromosome 4 using human-mouse somatic cell hybrids and Southern filter hybridization of cell hybrid DNA. To identify IL2, a recombinant DNA probe ( pIL2 - 50A ) was used which contained a human interleukin 2 cDNA insert which hybridized to a 3.5-kb fragment in human DNA when cleaved with the restriction enzyme EcoRI.

UI MeSH Term Description Entries
D007376 Interleukin-2 A soluble substance elaborated by antigen- or mitogen-stimulated T-LYMPHOCYTES which induces DNA synthesis in naive lymphocytes. IL-2,Lymphocyte Mitogenic Factor,T-Cell Growth Factor,TCGF,IL2,Interleukin II,Interleukine 2,RU 49637,RU-49637,Ro-23-6019,Ro-236019,T-Cell Stimulating Factor,Thymocyte Stimulating Factor,Interleukin 2,Mitogenic Factor, Lymphocyte,RU49637,Ro 23 6019,Ro 236019,Ro236019,T Cell Growth Factor,T Cell Stimulating Factor
D009693 Nucleic Acid Hybridization Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503) Genomic Hybridization,Acid Hybridization, Nucleic,Acid Hybridizations, Nucleic,Genomic Hybridizations,Hybridization, Genomic,Hybridization, Nucleic Acid,Hybridizations, Genomic,Hybridizations, Nucleic Acid,Nucleic Acid Hybridizations
D010957 Plasmids Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS. Episomes,Episome,Plasmid
D002460 Cell Line Established cell cultures that have the potential to propagate indefinitely. Cell Lines,Line, Cell,Lines, Cell
D002874 Chromosome Mapping Any method used for determining the location of and relative distances between genes on a chromosome. Gene Mapping,Linkage Mapping,Genome Mapping,Chromosome Mappings,Gene Mappings,Genome Mappings,Linkage Mappings,Mapping, Chromosome,Mapping, Gene,Mapping, Genome,Mapping, Linkage,Mappings, Chromosome,Mappings, Gene,Mappings, Genome,Mappings, Linkage
D002905 Chromosomes, Human, 4-5 The large, submetacentric human chromosomes, called group B in the human chromosome classification. This group consists of chromosome pairs 4 and 5. Chromosomes B,Group B Chromosomes,Chromosome, Group B,Chromosomes, Group B,Group B Chromosome
D004247 DNA A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine). DNA, Double-Stranded,Deoxyribonucleic Acid,ds-DNA,DNA, Double Stranded,Double-Stranded DNA,ds DNA
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006822 Hybrid Cells Any cell, other than a ZYGOTE, that contains elements (such as NUCLEI and CYTOPLASM) from two or more different cells, usually produced by artificial CELL FUSION. Somatic Cell Hybrids,Cell Hybrid, Somatic,Cell Hybrids, Somatic,Cell, Hybrid,Cells, Hybrid,Hybrid Cell,Hybrid, Somatic Cell,Hybrids, Somatic Cell,Somatic Cell Hybrid
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

Related Publications

T Shows, and R Eddy, and L Haley, and M Byers, and M Henry, and T Fujita, and H Matsui, and T Taniguchi
January 1984, Cancer investigation,
T Shows, and R Eddy, and L Haley, and M Byers, and M Henry, and T Fujita, and H Matsui, and T Taniguchi
January 1983, Proceedings of the National Academy of Sciences of the United States of America,
T Shows, and R Eddy, and L Haley, and M Byers, and M Henry, and T Fujita, and H Matsui, and T Taniguchi
January 1993, Cytogenetics and cell genetics,
T Shows, and R Eddy, and L Haley, and M Byers, and M Henry, and T Fujita, and H Matsui, and T Taniguchi
November 1994, In vitro cellular & developmental biology. Animal,
T Shows, and R Eddy, and L Haley, and M Byers, and M Henry, and T Fujita, and H Matsui, and T Taniguchi
January 1993, Genomics,
T Shows, and R Eddy, and L Haley, and M Byers, and M Henry, and T Fujita, and H Matsui, and T Taniguchi
July 1987, Annals of human genetics,
T Shows, and R Eddy, and L Haley, and M Byers, and M Henry, and T Fujita, and H Matsui, and T Taniguchi
October 1994, Cellular immunology,
T Shows, and R Eddy, and L Haley, and M Byers, and M Henry, and T Fujita, and H Matsui, and T Taniguchi
December 1988, The Journal of biological chemistry,
T Shows, and R Eddy, and L Haley, and M Byers, and M Henry, and T Fujita, and H Matsui, and T Taniguchi
May 1982, Proceedings of the National Academy of Sciences of the United States of America,
T Shows, and R Eddy, and L Haley, and M Byers, and M Henry, and T Fujita, and H Matsui, and T Taniguchi
January 1994, Cytogenetics and cell genetics,
Copied contents to your clipboard!