BIOMAT Database Logo BIOMAT Database Logo

[Pyridinol derivatives. (8) Synthesis and pharmacological activity of 4-phenylalkyl-2H-pyrido[3,2-b]-1,4-oxazin-3-one derivatives]. 1983

H Takeda, and H Fujita, and S Muroga, and S Suzuki, and K Hisamichi

UI MeSH Term Description Entries
D008297 Male Males
D010078 Oxazines Six-membered heterocycles containing an oxygen and a nitrogen.
D011725 Pyridines Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
D006168 Guinea Pigs A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research. Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea
D000700 Analgesics Compounds capable of relieving pain without the loss of CONSCIOUSNESS. Analgesic,Anodynes,Antinociceptive Agents,Analgesic Agents,Analgesic Drugs,Agents, Analgesic,Agents, Antinociceptive,Drugs, Analgesic
D000779 Anesthetics, Local Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. Anesthetics, Conduction-Blocking,Conduction-Blocking Anesthetics,Local Anesthetic,Anesthetics, Topical,Anesthetic, Local,Anesthetics, Conduction Blocking,Conduction Blocking Anesthetics,Local Anesthetics,Topical Anesthetics
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013329 Structure-Activity Relationship The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups. Relationship, Structure-Activity,Relationships, Structure-Activity,Structure Activity Relationship,Structure-Activity Relationships
D051379 Mice The common name for the genus Mus. Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus

Related Publications

H Takeda, and H Fujita, and S Muroga, and S Suzuki, and K Hisamichi
[Studies on pyridinol derivatives. III. Synthesis and pharmacological activity of 2H-pyrido [3,2-b]-1,4-oxazin-3-one derivatives].
February 1983, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
H Takeda, and H Fujita, and S Muroga, and S Suzuki, and K Hisamichi
[Studies on pyridinol derivatives. II. Synthesis and pharmacological activity of 2H-pyrido[3,2-b]-1,4-oxazin-3-one derivatives].
February 1983, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
H Takeda, and H Fujita, and S Muroga, and S Suzuki, and K Hisamichi
[Studies on pyridinol derivatives. X. Synthesis and pharmacological activity of 4-acyl-3,4-dihydro-2H-pyrido[3,2-b]-1,4-oxazine derivatives].
December 1983, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
H Takeda, and H Fujita, and S Muroga, and S Suzuki, and K Hisamichi
Identification of Morpholino-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-ones as Nonsteroidal Mineralocorticoid Antagonists.
February 2018, Journal of medicinal chemistry,
H Takeda, and H Fujita, and S Muroga, and S Suzuki, and K Hisamichi
Synthesis of 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as platelet aggregation inhibitors.
January 2012, Bioorganic & medicinal chemistry letters,
H Takeda, and H Fujita, and S Muroga, and S Suzuki, and K Hisamichi
Substituted pyrido[3,2-b]oxazin-3(4H)-ones: synthesis and evaluation of antinociceptive activity.
February 1998, Bioorganic & medicinal chemistry,
H Takeda, and H Fujita, and S Muroga, and S Suzuki, and K Hisamichi
Synthesis and pharmacological evaluations of novel 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as a new class of anti-cancer agents.
October 2011, European journal of medicinal chemistry,
H Takeda, and H Fujita, and S Muroga, and S Suzuki, and K Hisamichi
A one-pot synthesis of pyrido[2,3-b][1,4]oxazin-2-ones.
October 2003, The Journal of organic chemistry,
H Takeda, and H Fujita, and S Muroga, and S Suzuki, and K Hisamichi
4-Benzyl-7-chloro-2H-1,4-benz-oxazin-3(4H)-one.
April 2009, Acta crystallographica. Section E, Structure reports online,
H Takeda, and H Fujita, and S Muroga, and S Suzuki, and K Hisamichi
Design, synthesis and biological evaluation of novel series of 2H-benzo[b][1,4]oxazin-3(4H)-one and 2H-benzo[b][1,4]oxazine scaffold derivatives as PI3Kα inhibitors.
August 2018, Bioorganic & medicinal chemistry,
Copied contents to your clipboard!