Biomaterial Database

Portal blood flow in man during surgery, measured by a modification of the continuous thermodilution method. 1983

B Biber, and C Holm, and O Winsö, and B Gustavsson

The continuous thermodilution method was applied to measurement of peroperative portal venous blood flow in man in relation to hepatic surgery during steady-state enflurane nitrous oxide anaesthesia. Portal-vein catheterization through the umbilical vein for cytostatic administration and blood flow measurements was successful in 14 out of 17 patients with primary or secondary liver tumours. Mean portal blood flow was 1195 +/- 179 ml X min-1 (mean +/- SEM), corresponding to 17.6 +/- 2.9 ml X min-1 X kg-1 body weight. Mean oxygen consumption in the prehepatic splanchnic area was 0.27 +/- 0.04 ml X min-1 X kg-1. No significant complications were associated with the catheterization or flow recording procedures. The described method offers possibilities for haemodynamic and pharmacokinetic investigations in man.

UI	MeSH Term	Description	Entries
D008099	Liver	A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.	Livers
D008102	Liver Circulation	The circulation of BLOOD through the LIVER.	Hepatic Circulation,Circulation, Liver,Circulation, Hepatic
D008113	Liver Neoplasms	Tumors or cancer of the LIVER.	Cancer of Liver,Hepatic Cancer,Liver Cancer,Cancer of the Liver,Cancer, Hepatocellular,Hepatic Neoplasms,Hepatocellular Cancer,Neoplasms, Hepatic,Neoplasms, Liver,Cancer, Hepatic,Cancer, Liver,Cancers, Hepatic,Cancers, Hepatocellular,Cancers, Liver,Hepatic Cancers,Hepatic Neoplasm,Hepatocellular Cancers,Liver Cancers,Liver Neoplasm,Neoplasm, Hepatic,Neoplasm, Liver
D010101	Oxygen Consumption	The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)	Consumption, Oxygen,Consumptions, Oxygen,Oxygen Consumptions
D002404	Catheterization	Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.	Cannulation,Cannulations,Catheterizations
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013815	Thermodilution	Measurement of blood flow based on induction at one point of the circulation of a known change in the intravascular heat content of flowing blood and detection of the resultant change in temperature at a point downstream.	Thermodilutions