Support for the importance of psychosocial influences on smoking is limited because the evidence is primarily based on intervention studies which deal with self-selected and thus unrepresentative samples of smokers. There have been few comparisons with nonsmokers on these factors. In this study, we examine the role of psychosocial factors among a representative community sample of smokers and nonsmokers. Heavy smokers were distinguished from nonsmokers by only slightly higher levels of environmental stressors, less supportive social resources, and poorer psychological functioning. Light smokers did not differ from nonsmokers on these factors. Although stressors and resources were correlated with psychological functioning across all respondents, such relationships were not significantly stronger for either heavy or light smokers. These results suggest that psychosocial influences may have differential relevance during the different phases of smoking behavior such as initiation, maintenance, and cessation.