Chronic analgesic study on buprenorphine action in cancer pain. Comparison with pentazocine. 1983

V Ventafridda, and F De Conno, and G Guarise, and M Tamburini, and G Savio

Buprenorphine appears to have an analgesic effect (evaluated after a week of treatment) statistically superior to that of the comparative drug. On the whole, during buprenorphine treatment the normal activities of life of the individual patient improved. The percentage incidence of the side-effects is similar for the two drugs. Buprenorphine, however, caused less intense side-effects than pentazocine.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009019 Morphinans Compounds based on a partially saturated iminoethanophenanthrene, which can be described as ethylimino-bridged benzo-decahydronaphthalenes. They include some of the OPIOIDS found in PAPAVER that are used as ANALGESICS. Morphinan
D009369 Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. Benign Neoplasm,Cancer,Malignant Neoplasm,Tumor,Tumors,Benign Neoplasms,Malignancy,Malignant Neoplasms,Neoplasia,Neoplasm,Neoplasms, Benign,Cancers,Malignancies,Neoplasias,Neoplasm, Benign,Neoplasm, Malignant,Neoplasms, Malignant
D010146 Pain An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. Suffering, Physical,Ache,Pain, Burning,Pain, Crushing,Pain, Migratory,Pain, Radiating,Pain, Splitting,Aches,Burning Pain,Burning Pains,Crushing Pain,Crushing Pains,Migratory Pain,Migratory Pains,Pains, Burning,Pains, Crushing,Pains, Migratory,Pains, Radiating,Pains, Splitting,Physical Suffering,Physical Sufferings,Radiating Pain,Radiating Pains,Splitting Pain,Splitting Pains,Sufferings, Physical
D010423 Pentazocine The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97) Fortral,Lexir,Pentazocine Hydrochloride,Pentazocine Lactate,Talwin,Hydrochloride, Pentazocine,Lactate, Pentazocine
D002047 Buprenorphine A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use. 6029-M,Buprenex,Buprenorphine Hydrochloride,Buprex,Prefin,RX-6029-M,Subutex,Temgesic,Temgésic,6029 M,6029M,Hydrochloride, Buprenorphine,RX 6029 M,RX6029M
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

Related Publications

V Ventafridda, and F De Conno, and G Guarise, and M Tamburini, and G Savio
February 1982, Gan to kagaku ryoho. Cancer & chemotherapy,
V Ventafridda, and F De Conno, and G Guarise, and M Tamburini, and G Savio
January 1965, Anesthesia and analgesia,
V Ventafridda, and F De Conno, and G Guarise, and M Tamburini, and G Savio
October 1981, Masui. The Japanese journal of anesthesiology,
V Ventafridda, and F De Conno, and G Guarise, and M Tamburini, and G Savio
May 1986, International journal of clinical pharmacology, therapy, and toxicology,
V Ventafridda, and F De Conno, and G Guarise, and M Tamburini, and G Savio
January 1980, Journal of clinical pharmacology,
V Ventafridda, and F De Conno, and G Guarise, and M Tamburini, and G Savio
January 1990, Progress in clinical and biological research,
V Ventafridda, and F De Conno, and G Guarise, and M Tamburini, and G Savio
January 1983, British journal of anaesthesia,
V Ventafridda, and F De Conno, and G Guarise, and M Tamburini, and G Savio
January 1986, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
V Ventafridda, and F De Conno, and G Guarise, and M Tamburini, and G Savio
April 1969, Masui. The Japanese journal of anesthesiology,
V Ventafridda, and F De Conno, and G Guarise, and M Tamburini, and G Savio
June 1975, The British journal of clinical practice,
Copied contents to your clipboard!