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Plasma renin activity was determined by bioassay prior to, during and following a 2-hour infusion of norepinephrine into the renal artery in unilaterally nephrectomized dogs in order to examine the role of renin-angiotensin system in norepinephrine-induced ARF. ARF was induced in 5 of 8 dogs receiving 0.75 microgram/kg/min of norepinephrine, but not in the remaining 3 dogs and 2 dogs infused with 0.6 and 0.4 microgram/kg/min of norepinephrine. There proved no difference in plasma renin activity in renal venous blood between the dogs with and without ARF when followed up to 2 h after the discontinuation of the infusion. The same results were obtained when the plasma renin activity in the foreleg vein was followed at 24, 48 and 72 h after the infusion. The renin-angiotensin system does not seem to contribute to the reduction of renal function in norepinephrine-induced ARF in dogs.
Y Sasaki, and
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K Minai, and
R Shioji, and
T Furuyama, and
K Yoshinaga
October 1980,
The Journal of laboratory and clinical medicine,
Y Sasaki, and
Y Michimata, and
K Minai, and
R Shioji, and
T Furuyama, and
K Yoshinaga
November 1972,
AMB : revista da Associacao Medica Brasileira,
Y Sasaki, and
Y Michimata, and
K Minai, and
R Shioji, and
T Furuyama, and
K Yoshinaga
April 1965,
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Y Sasaki, and
Y Michimata, and
K Minai, and
R Shioji, and
T Furuyama, and
K Yoshinaga
August 1972,
Klinische Wochenschrift,
Y Sasaki, and
Y Michimata, and
K Minai, and
R Shioji, and
T Furuyama, and
K Yoshinaga
October 1973,
The Journal of laboratory and clinical medicine,
Y Sasaki, and
Y Michimata, and
K Minai, and
R Shioji, and
T Furuyama, and
K Yoshinaga
January 1972,
Klinische Wochenschrift,
Y Sasaki, and
Y Michimata, and
K Minai, and
R Shioji, and
T Furuyama, and
K Yoshinaga
January 1980,
International urology and nephrology,
Y Sasaki, and
Y Michimata, and
K Minai, and
R Shioji, and
T Furuyama, and
K Yoshinaga
August 1973,
Pflugers Archiv : European journal of physiology,
Y Sasaki, and
Y Michimata, and
K Minai, and
R Shioji, and
T Furuyama, and
K Yoshinaga
July 1947,
American journal of veterinary research,
Y Sasaki, and
Y Michimata, and
K Minai, and
R Shioji, and
T Furuyama, and
K Yoshinaga
January 1972,
Investigative radiology,
