-transparent.png){kind=logo}
The effect of graded oral doses of trimethyldesoxy-prostaglandin E2 (Ro 21-6937) on basal acid secretion in healthy volunteers was tested over a time period of 6 h. Basal acid output was reduced by 80% after 1500 micrograms Ro 21-6937. Half-maximal inhibition was achieved by 700 micrograms Ro 21-6937. 250 micrograms of this prostaglandin E2 analog showed no detectable antisecretory activity.
Related Publications
H G Dammann, and
P Müller, and
B Simon
January 1983,
British journal of pharmacology,
H G Dammann, and
P Müller, and
B Simon
May 1978,
The American journal of physiology,
H G Dammann, and
P Müller, and
B Simon
February 1976,
The American journal of physiology,
H G Dammann, and
P Müller, and
B Simon
March 1973,
The Journal of physiology,
H G Dammann, and
P Müller, and
B Simon
October 1980,
Obstetrical & gynecological survey,
H G Dammann, and
P Müller, and
B Simon
July 1987,
Gastroenterology,
H G Dammann, and
P Müller, and
B Simon
March 1969,
Nature,
H G Dammann, and
P Müller, and
B Simon
January 2003,
Prostaglandins & other lipid mediators,
H G Dammann, and
P Müller, and
B Simon
January 1992,
Gynecologic and obstetric investigation,
H G Dammann, and
P Müller, and
B Simon
October 1979,
The American journal of physiology,
