Effect of hypercalcaemia on adrenocortical and growth hormone secretion. 1983

I Zofková, and M Neradilová, and L Stárka, and I Kimlová, and A Simecková

The authors investigated in 19 healthy women changes in the plasma levels of cortisol and growth hormone during acute hypercalcaemia induced by a load of 8.9 mg Ca2+/kg body weight, administered as intravenous infusion and the effect of hypercalcaemia on the adrenocortical and somatotrophic secretory reserve assessed by the test with insulin hypoglycaemia. Hypercalcaemia causes a rise of the basal cortisol plasma level starting at the 90th minute from the onset of the infusion when the calcium level reaches values of 2.99 mmol/l. The adrenocortical secretory reserve is, however, significantly reduced by hypercalcaemia. Hypercalcaemia does not affect growth levels nor the somatotrophic secretory reserve.

UI MeSH Term Description Entries
D008274 Magnesium A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002118 Calcium A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. Coagulation Factor IV,Factor IV,Blood Coagulation Factor IV,Calcium-40,Calcium 40,Factor IV, Coagulation
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006854 Hydrocortisone The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions. Cortef,Cortisol,Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-,11-Epicortisol,Cortifair,Cortril,Epicortisol,Hydrocortisone, (11 alpha)-Isomer,Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer,11 Epicortisol
D006934 Hypercalcemia Abnormally high level of calcium in the blood. Milk-Alkali Syndrome,Hypercalcemias,Milk Alkali Syndrome,Syndrome, Milk-Alkali
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000305 Adrenal Cortex Hormones HORMONES produced by the ADRENAL CORTEX, including both steroid and peptide hormones. The major hormones produced are HYDROCORTISONE and ALDOSTERONE. Adrenal Cortex Hormone,Corticoid,Corticoids,Corticosteroid,Corticosteroids,Cortex Hormone, Adrenal,Hormone, Adrenal Cortex,Hormones, Adrenal Cortex
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

I Zofková, and M Neradilová, and L Stárka, and I Kimlová, and A Simecková
July 1990, Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete,
I Zofková, and M Neradilová, and L Stárka, and I Kimlová, and A Simecková
December 1963, The Journal of endocrinology,
I Zofková, and M Neradilová, and L Stárka, and I Kimlová, and A Simecková
November 1964, The Journal of endocrinology,
I Zofková, and M Neradilová, and L Stárka, and I Kimlová, and A Simecková
August 1968, The American journal of physiology,
I Zofková, and M Neradilová, and L Stárka, and I Kimlová, and A Simecková
October 1983, Polski tygodnik lekarski (Warsaw, Poland : 1960),
I Zofková, and M Neradilová, and L Stárka, and I Kimlová, and A Simecková
November 1981, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
I Zofková, and M Neradilová, and L Stárka, and I Kimlová, and A Simecková
February 1957, Endocrinology,
I Zofková, and M Neradilová, and L Stárka, and I Kimlová, and A Simecková
January 1960, World review of nutrition and dietetics,
I Zofková, and M Neradilová, and L Stárka, and I Kimlová, and A Simecková
June 1977, British medical journal,
I Zofková, and M Neradilová, and L Stárka, and I Kimlová, and A Simecková
January 1991, Hormone research,
Copied contents to your clipboard!