Disinfection of gastrointestinal fibrescopes--evaluation of the disinfectants Dettox and Gigasept. 1983

H J O'Connor, and C S Steele, and J Price, and C Lincoln, and A T Axon

The disinfectant solutions Dettox (based on a quaternary ammonium compound) and Gigasept (based on succine dialdehyde) were evaluated during disinfection procedures with a new disinfecting apparatus for gastrointestinal fibrescopes. Thorough disinfection was achieved after 2 minutes using Dettox 8% or Gigasept 10%; persistent fibrescope contamination with Gram-negative organisms was found after disinfection with Dettox 4% or Gigasep 5%. No adverse effects in endoscopy staff or damage to fibrescopes were seen. Adequate disinfection of endoscopic equipment prevents endoscopy-related infection and can be readily achieved by trained endoscopy staff using rapidly bactericidal disinfectants.

UI MeSH Term Description Entries
D004202 Disinfectants Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed) Biocide,Disinfectant,Biocides
D004338 Drug Combinations Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture. Drug Combination,Combination, Drug,Combinations, Drug
D005336 Fiber Optic Technology The technology of transmitting light over long distances through strands of glass or other transparent material. Fiber Optic Technologies,Optic Technologies, Fiber,Optic Technology, Fiber,Technologies, Fiber Optic,Technology, Fiber Optic
D005557 Formaldehyde A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717) Formalin,Formol,Methanal,Oxomethane
D005663 Furans Compounds with a 5-membered ring of four carbons and an oxygen. They are aromatic heterocycles. The reduced form is tetrahydrofuran. Tetrahydrofurans
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000447 Aldehydes Organic compounds containing a carbonyl group in the form -CHO. Aldehyde
D000644 Quaternary Ammonium Compounds Derivatives of ammonium compounds, NH4+ Y-, in which all four of the hydrogens bonded to nitrogen have been replaced with hydrocarbyl groups. These are distinguished from IMINES which are RN Quaternary Ammonium Compound,Ammonium Compound, Quaternary,Ammonium Compounds, Quaternary,Compound, Quaternary Ammonium
D020699 Gastroscopes Endoscopes used for examining the interior of the stomach. Gastroscope

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